Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/archdischild-2019-318672 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessment of potentially unnecessary antibiotic use for suspected urinary tract infections in nursing homes using a simplified algorithm.
Expert Rev Anti Infect Ther
January 2025
Department of Social Medicine, School of Medicine, University of Crete, Heraklio, Crete, Greece.
Background: Nursing home (NH) residents are frequently treated with antibiotics for urinary tract infections (UTIs), often due to overdiagnosis. The aim of this study was to evaluate the proportion of potentially unnecessary antibiotic use for suspected UTIs in NHs across eight European countries.
Research Design And Methods: Over a three-month period (February to April 2024), NH professionals recorded information on all antibiotic treatments for UTIs using a specific registration chart.
ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro.
Nat Microbiol
January 2025
Synthetic and Systems Biology Unit, Institute of Biochemistry, HUN-REN Biological Research Centre, National Laboratory of Biotechnology, Szeged, Hungary.
Despite ongoing antibiotic development, evolution of resistance may render candidate antibiotics ineffective. Here we studied in vitro emergence of resistance to 13 antibiotics introduced after 2017 or currently in development, compared with in-use antibiotics. Laboratory evolution showed that clinically relevant resistance arises within 60 days of antibiotic exposure in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa, priority Gram-negative ESKAPE pathogens.
View Article and Find Full Text PDFNeurophysiological Insights into the Pathophysiology of Stiff-Person Spectrum Disorders.
Mov Disord Clin Pract
January 2025
Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, United Kingdom.
Background: Stiff Person Spectrum Disorders (SPSD) are classically defined by the presence of muscle stiffness, spasms and hyperactivity of the central nervous system. There is a notable correlation between neurophysiological features and the clinical hallmark of SPSD, which has greatly encouraged the use of these techniques for diagnostic purposes. Besides, electrophysiological techniques allow for a functional evaluation of the 'hyperactivity of the CNS', thus offering the opportunity to clarify the mechanisms underlying this disorder.
View Article and Find Full Text PDFGenomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens.
Cell
October 2024
Synthetic and Systems Biology Unit, Institute of Biochemistry, National Laboratory of Biotechnology, HUN-REN Biological Research Centre, Temesvári Krt. 62, 6726 Szeged, Hungary; HCEMM-BRC Translational Microbiology Research Group, Budapesti út 9, 6728 Szeged, Hungary. Electronic address:
Article Synopsis
- Phage therapy is a new way to fight germs that are super tough against antibiotics, especially in hospitals.
- Scientists are figuring out how to create special mixes of viruses called phages that can target specific strains of a dangerous germ called Acinetobacter baumannii.
- By studying where these germs are found in the world, researchers can prepare special phage treatments for different regions, which has been shown to work well in tests and with animals.
[Therapeutic challenges in difficult-to-treat, penetrating Crohn's disease - a multidisciplinary approach].
Orv Hetil
August 2024
1 Szegedi Tudományegyetem, Szent-Györgyi Albert Orvostudományi Kar, Klinikai Központ, Belgyógyászati Klinika, Gasztroenterológiai Centrum Szeged, Kálvária sgt. 57., 6725 Magyarország.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!