In the western United States, poisonous plants most often affect grazing livestock, and the related livestock losses are estimated to cost the grazing livestock industry more than $200 million annually. Many of these toxic plants contain neurotoxins that damage or alter the function of neurologic cells in the central and peripheral nervous systems. The objectives of this article are to present common North American neurotoxic plants, including conditions of poisoning, clinical disease, pathologic changes, and available diagnostics, to identify poisoned animals and the potential prognosis for poisoned animals.
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http://dx.doi.org/10.1016/j.cvfa.2020.08.002 | DOI Listing |
Toxins (Basel)
January 2025
Department of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Sciences, Poznan University of Life Sciences, Wolynska St. 35, 60-637 Poznan, Poland.
Food contamination with mycotoxin-producing fungi increases the risk of many diseases, including neurological diseases closely related to the neurotoxicity of these toxins. Based on the latest literature data, we presented the association of common mycotoxins with neurological diseases. Articles from 2001 to 2024 were analyzed.
View Article and Find Full Text PDFMol Neurobiol
January 2025
School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, 226001, People's Republic of China.
Growing evidence suggests that plant compounds are emerging as a tremendous source for slowing the onset and progression of Alzheimer's disease (AD). Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid with some hypoglycemic, anticancer, and antiinflammatory activities. However, the pharmacological effects of UNA on AD are still unknown.
View Article and Find Full Text PDFCurr Res Toxicol
December 2024
Institute of Toxicology, College of Preventive Medicine, Army Medical University, Chongqing 400038, China.
Rotenone is a natural compound from plants. It is widely used in pesticides because of highly toxic to insects and fish. However, lots of research has reported that rotenone has neurotoxic effects in humans.
View Article and Find Full Text PDFHeliyon
July 2024
Department of Anesthesia, People's Liberation Army the General Hospital of Western Theater Command, Chengdu, Sichuan, 610083, China.
Background: Ropivacaine (Rop) is a local anesthetic that is widely used but is also potentially harmful. Quercetin (Quer) is a flavonoid component found in many plants and traditional Chinese medicines. It possesses anti-oxidant, anti-inflammatory, antitumor, and neuroprotective properties as a pharmaceutical.
View Article and Find Full Text PDFMycotoxin Res
February 2025
Department of Human, Biological, and Translational Medical Sciences, School of Medicine, University of Namibia, Windhoek, Namibia.
Mycotoxin exposure from contaminated food is a significant global health issue, particularly among vulnerable children. Given limited data on mycotoxin exposure among Namibian children, this study investigated mycotoxin types and levels in foods, evaluated dietary mycotoxin exposure from processed cereal foods in children under age five from rural households in Oshana region, Namibia. Mycotoxins in cereal-based food samples (n = 162) (mahangu flour (n = 35), sorghum flour (n = 13), mahangu thin/thick porridge (n = 54), oshikundu (n = 56), and omungome (n = 4)) were determined by liquid chromatography-tandem mass spectrometry.
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