Application of an inhibitor-based probe to reveal the distribution of membrane PSMA in dSTORM imaging.

Chem Commun (Camb)

Research Center of Biomembranomics, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.

Published: November 2020

Relying on an inhibitor-based probe, we reveal the clustered distribution of membrane PSMA by dSTORM imaging and uncover its potential interaction with folate receptor. This inhibitor-based strategy realizes more accurate labeling than antibody labeling, which would make it a powerful tool in the field of dSTORM imaging.

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http://dx.doi.org/10.1039/d0cc04889eDOI Listing

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