AI Article Synopsis

  • The study aimed to evaluate the visual dysfunction characteristics in patients suffering from carbon monoxide (CO) poisoning, analyzing 436 individuals over several years.
  • Findings revealed that patients exhibited a variety of ocular symptoms, including local pain and visual field defects, with underlying issues like optic nerve damage and retinal problems being prominent.
  • The research concluded that visual dysfunction was common and persistent in CO poisoning cases, with a need for improved ophthalmological assessments and treatments due to the prolonged and often poor prognoses.

Article Abstract

Purpose: The aim of the present study was to analyze the clinical characteristics of visual dysfunction in patients with carbon monoxide (CO) poisoning.

Methods: A total of 436 patients with CO poisoning were enrolled in our hospital from October 2012 to December 2018, including 193 patients with moderate poisoning (MP group), 165 with severe poisoning (SP group), and 78 with delayed encephalopathy (DE group). The clinical characteristics of visual dysfunction in patients with CO poisoning were analyzed through the collection of medical history, regular physical examination, brain magnetic resonance imaging (MRI), ophthalmological examination, the National Eye Institute Visual Function Questionnaire (NEI-VFQ), and its influencing factors.

Results: Some patients in the three groups had visual dysfunction. The main ocular symptoms were local pain, eye movement disorder, and visual field defect. The key pathological factors were keratopathy, retinal nerve cell damage, optic nerve damage, retinal vascular disease, macular disease, and occipital visual center damage. The clinical symptoms of visual dysfunction after CO poisoning lasted for a long time (>12 months) and were not completely consistent with the positive results of the ophthalmological examination. A few sequelae of ophthalmology were still left after the help of medicine.

Conclusion: The incidence of visual dysfunction in patients with CO poisoning was high, the clinical symptoms were rich and diverse, the duration of disease was long, and the prognosis was poor. Thus, the relevant ophthalmological examination and intervention treatment should be perfected as soon as possible.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528143PMC
http://dx.doi.org/10.1155/2020/9537360DOI Listing

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