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Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT): Multicenter Study. | LitMetric

AI Article Synopsis

  • The study aimed to evaluate the effectiveness of chest CT and RT-PCR tests for COVID-19 in asymptomatic surgical patients.
  • The research involved 2,093 patients across 14 centers, revealing a low positive yield of COVID-19 cases—1.5% for combined testing, 0.7% for CT, and 1.1% for RT-PCR.
  • Results indicated that while preoperative screening helped ensure safety in surgeries, the value of chest CT testing was minimal compared to RT-PCR, particularly as community COVID-19 prevalence increased.

Article Abstract

Objective: To determine the yield of preoperative screening for COVID-19 with chest CT and RT-PCR in patients without COVID-19 symptoms.

Summary Of Background Data: Many centers are currently screening surgical patients for COVID-19 using either chest CT, RT-PCR or both, due to the risk for worsened surgical outcomes and nosocomial spread. The optimal design and yield of such a strategy are currently unknown.

Methods: This multicenter study included consecutive adult patients without COVID-19 symptoms who underwent preoperative screening using chest CT and RT-PCR before elective or emergency surgery under general anesthesia.

Results: A total of 2093 patients without COVID-19 symptoms were included in 14 participating centers; 1224 were screened by CT and RT-PCR and 869 by chest CT only. The positive yield of screening using a combination of chest CT and RT-PCR was 1.5% [95% confidence interval (CI): 0.8-2.1]. Individual yields were 0.7% (95% CI: 0.2-1.1) for chest CT and 1.1% (95% CI: 0.6-1.7) for RT-PCR; the incremental yield of chest CT was 0.4%. In relation to COVID-19 community prevalence, up to ∼6% positive RT-PCR was found for a daily hospital admission rate >1.5 per 100,000 inhabitants, and around 1.0% for lower prevalence.

Conclusions: One in every 100 patients without COVID-19 symptoms tested positive for SARS-CoV-2 with RT-PCR; this yield increased in conjunction with community prevalence. The added value of chest CT was limited. Preoperative screening allowed us to take adequate precautions for SARS-CoV-2 positive patients in a surgical population, whereas negative patients needed only routine procedures.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668335PMC
http://dx.doi.org/10.1097/SLA.0000000000004218DOI Listing

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