Aim: To evaluate clinical performance and side effects of two commercially available 0.2% chlorhexidine mouthwashes after periodontal surgery, one with (test) and one without (control) an anti-discoloration system.
Materials And Methods: This single-centre, crossover clinical trial included 38 patients undergoing two sessions of periodontal flap surgery. The participants used two different 0.2% chlorhexidine products, one with and one without an anti-discoloration system, in the 14-day post-operative periods. Plaque, gingival inflammation, tooth staining, side effects and patient preference were evaluated.
Results: The control mouthwash (without an anti-discolouring system) produced significantly lower plaque (p = 0.02) and gingival index (p = 0.01) compared to the test mouthwash. The test mouthwash produced significantly less staining in the gingival (p = 0.002) and approximal areas (p = 0.0004), but no difference was detected in the buccal area of the teeth. The patients did not show preference for any of the mouthwashes.
Conclusion: Chlorhexidine mouthwash without an anti-discoloration system resulted in significantly lowered plaque and gingival index compared to chlorhexidine mouthwash with an anti-discoloration following periodontal surgery. No difference in patient preference was found despite less side effects produced by the chlorhexidine mouthwash with the anti-discoloration system.
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http://dx.doi.org/10.1111/jcpe.13382 | DOI Listing |
Dent J (Basel)
November 2024
Department of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio, 66100 Chieti, Italy.
Little has been written in the literature about the clinical comparison between the single use of chlorhexidine (CHX) and its combination with cetylpyridinium chloride (CPC). The purpose of this study is to compare the clinical effectiveness of two at-home antiseptic regimens. : Healthy subjects scheduled for dental surgery were enrolled.
View Article and Find Full Text PDFHeliyon
December 2024
Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, 10400, Thailand.
Objective: The purpose of this study was to examine the effect of several antiseptic mouthwashes on the dentin microtensile bond strength of self-etch adhesive, considering the influence of rinsing with water.
Methods: Forty flat dentin surfaces were produced by sectioning sound extracted third molars. They were randomly divided into four main groups: (1) artificial saliva (control); (2) 1 % hydrogen peroxide; (3) 0.
BMC Pregnancy Childbirth
December 2024
School of Public Health, University of Ghana, P.O. Box LG 25, Legon, Accra, Ghana.
Background: The Government of Ghana in 2017 included chlorhexidine (CHX) digluconate 7.1% gel in the essential medicines list to replace methylated spirit for umbilical cord care. However, there are limited studies around the use of the CHX gel.
View Article and Find Full Text PDFMol Biol Rep
December 2024
Department of Aquaculture, Faculty of Aquaculture, Van YüzüncüYıl University, Van, Turkey.
Objectives: This study aimed to investigate the effects of andiz extract on wound healing and compare it with saline and chlorhexidine gluconate. Microbial DNA load was used to evaluate its antibacterial effects, and gene expression methods were used to assess its contribution to cytokine release and wound healing.
Methods And Results: A standardized wound site was created with a 3 mm diameter punch on 32 male Wistar albino rats.
J Oral Microbiol
December 2024
School of Health Professions, Faculty of Health, University of Plymouth, Plymouth, UK.
Background: Propolis mouthwash (PROP-M) has demonstrated antibacterial properties like those of chlorhexidine mouthwash (CHX-M). However, its impact on the abundance of oral nitrite-producing species (NPS) and nitrite-producing activity (NPA) remains unexplored.
Methods: Forty-five healthy individuals were randomised into 2 groups to rinse their mouth twice a day for seven days with either CHX-M ( = 21) or PROP-M ( = 24).
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