Rationale: Pulmonary sequestration (PS) presenting with elevated serum tumor markers is rare, and it might be misdiagnosed as malignancy.
Patient Concerns: A 26-year-old asymptomatic male patient was admitted because the x-ray showed an intrathoracic lesion. Meanwhile, the serum neuron-specific enolase (NSE) was elevated. Three-dimensional computed tomography angiography revealed an isolated feeding vessel arising from the aorta.
Diagnoses: Extralobular PS was confirmed by computed tomography angiography and postoperative pathological staining.
Interventions: Two-port thoracoscopic resection of the sequestrated lobe was performed.
Outcomes: The serum NSE decreased to within the normal range and persisted during the follow up of 10 months.
Lessons: A thorough work-up should be considered for the PS patients presenting with abnormal serum NSE. Detailed knowledge regarding the relationship between NSE and PS necessitates further studies.
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| http://dx.doi.org/10.1097/MD.0000000000022574 | DOI Listing |
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