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Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country. | LitMetric
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Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country.

Lishuang Shen Jennifer Dien Bard Jaclyn A Biegel Alexander R Judkins Xiaowu Gai

Front Microbiol

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA, United States.

Published: September 2020

Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness of existing travel restriction policies and public health measures in reducing the transmission of SARS-CoV-2.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509426PMC
http://dx.doi.org/10.3389/fmicb.2020.573430DOI Listing

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