Water intoxication is a life-threatening disorder accompanied by brain function impairment due to severe dilutional hyponatremia. We present a young woman who had multiple emergency admissions with severe dyselectrolytemias involving several electrolytes. Further assessment revealed a long history of chronic polydipsia and episodic water intoxication. Her serum electrolytes were normal after an overnight fluid fast. She had no further admissions after discussion and counseling concerning excessive water drinking. This case emphasizes the importance of obtaining an accurate fluid intake history in cases of hyponatremia and multiple electrolyte disturbances.
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http://dx.doi.org/10.7759/cureus.10665 | DOI Listing |
J Equine Vet Sci
January 2025
Department of Anesthesiology and Surgery, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Mănăştur St. 3-5, 400372 Cluj-Napoca, Romania.
Ethylene glycol toxicosis is a common occurrence in dogs and cats but has been reported in other species as well. Up to date, only one case of ethylene glycol toxicosis has been described in horses, and specific guidelines for treating ethylene glycol intoxication in this species are not available. Here we describe the case of 39 sport horses that ingested water contaminated with ethylene glycol.
View Article and Find Full Text PDFJ Bacteriol
December 2024
Department of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Unlabelled: The ability to treat infections is threatened by the rapid emergence of antibiotic resistance among pathogenic microbes. Therefore, new antimicrobials are needed. Here we evaluate mannitol-1-phosphate 5-dehydrogenase (MtlD) as a potential new drug target.
View Article and Find Full Text PDFBMC Surg
December 2024
2Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: The study aims to investigate the application of surgical vaginoscopy via a no-touch hysteroscopic approach for the management of female genital polyps. The primary objective is to assess the feasibility of this technique in treating intrauterine pathologies in both pregnant and non-pregnant women.
Methods: A total of forty-six patients diagnosed with genital polyps underwent operative vaginoscopy at a university-affiliated hospital between April 1, 2017 and May 31, 2023.
Exp Gerontol
December 2024
Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address:
Aluminum chloride (AlCl), a known neurotoxic and Alzheimerogenic metal disrupts redox homeostasis which plays a pivotal role in pathophysiology of neurodegenerative disorders, particularly cognitive decline. The current study was designed to unveil the long-term neuroprotective outcomes and efficacy of CoQ10 and curcumin low dose (100 mg/kg each) combination in 18-months old geriatric male Balb/c mice subjected to AlCl-prompted memory derangements (200 mg/kg in water bottles) for 28 days. The neuroprotective properties driven by antioxidant mechanisms were assessed via observing cellular pathology in key-memory related brain regions including the cornuammonis (CA3 and DG) and cortex 2/3 layer.
View Article and Find Full Text PDFPol Merkur Lekarski
December 2024
I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE.
Objective: . Aim: To investigate changes in oxidative stress indicators in rats under conditions of long-term ethanol exposure.
Patients And Methods: Materials and Methods: We studied the effect of prolonged exposure to ethanol on the activity of free radical processes in the gonads of rats of both sexes.
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