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| http://dx.doi.org/10.1002/cld.1028 | DOI Listing |
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The transcription factor YbdO attenuates the pathogenicity of avian pathogenic Escherichia coli by regulating oxidative stress response.
BMC Microbiol
December 2024
College of Agriculture and Forestry, Linyi University, Linyi, 276005, Shandong, China.
Avian pathogenic Escherichia coli (APEC) is a significant pathogen infecting poultry that is responsible for high mortality, morbidity and severe economic losses to the poultry industry globally, posing a substantial risk to the health of poultry. APEC encounters reactive oxygen species (ROS) during the infection process and thus has evolved antioxidant defense mechanisms to protect against oxidative damage. The imbalance of ROS production and antioxidant defenses is known as oxidative stress, which results in oxidative damage to proteins, lipids and DNA, and even bacterial cell death.
View Article and Find Full Text PDFImpact of Patient Volume on Iodinated Contrast Material Waste with Multidose Contrast Injectors.
Acad Radiol
December 2024
Department of Radiological Sciences, University of California Irvine, Orange, CA 92868. Electronic address:
Background: Multidose iodinated contrast media (ICM) injectors have shown promise in reducing ICM waste. This study aims to evaluate the impact of patient volume on ICM waste reduction in multidose injectors.
Methods: CT studies performed over one-year period with a multidose injector at our emergency CT unit.
Microsatellites markers fostering the understanding of malaria parasite biology, epidemiology and population genetics.
Diagn Microbiol Infect Dis
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Department of Molecular Epidemiology, National Institute of Malaria Research, Sector-8, Dwarka, Delhi 110077, India. Electronic address:
Microsatellites, or simple sequence repeats (SSRs), are short tandemly repeated DNA sequences widely dispersed throughout the genome. Their high variability, co-dominant inheritance, and ease of detection make them valuable genetic markers, frequently used to study genetic diversity, population structure, and evolutionary processes. In the context of malaria research, particularly with Plasmodium falciparum (P.
View Article and Find Full Text PDFRECENT FOCUS IN NON-SELEX-COMPUTATIONAL APPROACH FOR DE NOVO APTAMER DESIGN: A MINI REVIEW.
Anal Biochem
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Department of Biochemistry, Kampala International University-Western Campus, Ishaka, Uganda.
Aptamers, single-stranded nucleic acids that bind to specific targets with high affinity and specificity, hold significant promise in various biomedical and biotechnological applications. The traditional method of aptamer selection, SELEX (Systematic Evolution of Ligands by EXponential Enrichment) takes a lot of work and time. Recent advancements in computational methods have revolutionized aptamer design, offering efficient and effective alternatives.
View Article and Find Full Text PDFRemoval of phthalate esters by integrated adsorption and biodegradation using improved performance of lipase@MOFs.
Environ Pollut
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Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Diseases and Key Laboratory of Biomedicine in Gene Diseases and Health of Anhui Higher Education Institutes, College of Life Sciences, Anhui Normal University, Wuhu 241000, Anhui, China. Electronic address:
Phthalate esters (PAEs) are broadly utilized as plasticizers in industrial products, posing a significant threat to ecological security and human health. Lipase is a kind of green biocatalyst with the ability to degrade PAEs, but its application is limited due to its low stability and poor reusability. Herein, lipase from Candida rugosa (CRL) was immobilized into an organic ligand replacement MOFs (MAF-507) and cysteine modification and glutaraldehyde cross-linking were simultaneously performed to synthesize immobilized lipase (Cys-CRL@GA@MAF-507) using a one-pot method.
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