A Rare Case of Cerebellar Progressive Multifocal Leukoencephalopathy due to Idiopathic CD4 Lymphocytopenia.

Mult Scler Relat Disord

Neurology, 740 S. Limestone, J-455, Lexington, KY 40536, United States.

Published: November 2020

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disorder caused by reactivation of JC virus during a time of cell mediated immune suppression. One potential rare cause of PML is Idiopathic CD4 lymphocytopenia (ICL) in which there is an unexplained deficit of CD4 T cells. We present a case of cerebellar PML in the absence of known immunosuppression leading to the diagnosis of ICL.

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Source
http://dx.doi.org/10.1016/j.msard.2020.102531DOI Listing

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