[Fatal invasive pulmonary aspergillosis in a patient with multiple non-classic risk factors].

Background: Pulmonary aspergillosis is a severe invasive infection that mainly affects immunocompromised patients, causing a great mortality.

Clinical Case: We present a male patient with chronic ethilism, diabetes mellitus, and work exposure of inhalated harmful chemicals, who had a fatal outcome, that even when not presenting typical risk factors, developed a clinical presentation compatible, and mycological evaluation that support the diagnosis of a probably invasive pulmonary aspergillosis.

Conclusion: The effect of the combination of the described non-typical situations as predisposing factors for pulmonary aspergillosis requires further research, given that they are non-typical factors.