Should we STOP immunosuppression for IgA nephropathy? Long-term outcomes from the STOP-IgAN trial.

Kidney Int

Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; John Walls Renal Unit, University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address:

Published: October 2020

The role of immunosuppression in the management of IgA nephropathy remains highly controversial. The Supportive Versus Immunosuppressive Therapy for the Treatment of Progressive IgA Nephropathy (STOP-IgAN) trial suggested that there was no benefit with the addition of immunosuppression to intensive supportive care, in terms of renal outcome. In this edition of Kidney International, Rauen et al. report long-term outcomes from the STOP-IgAN trial.

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http://dx.doi.org/10.1016/j.kint.2020.05.033DOI Listing

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