AI Article Synopsis
- Hemispherectomy is a surgical procedure primarily for treating severe epilepsy in young children, significantly revised since its original description.
- It effectively addresses various epileptic syndromes such as hemimegalencephaly, Rasmussen's encephalitis, and Sturge-Weber syndrome, showing high success in reducing seizures.
- Over the years, advancements in the procedure have decreased associated risks, but conditions like hemimegalencephaly can still raise morbidity and affect success rates, indicating the need for more research on outcome predictors.
Article Abstract
Hemispherectomy is a unique epilepsy surgery procedure that has undergone significant modification and evolution since Dandy's early description. This procedure is mainly indicated to treat early childhood and infancy medically intractable epilepsy. Various epileptic syndromes have been treated with this procedure, including hemimegalencephaly (HME), Rasmussen's encephalitis, Sturge-Weber syndrome (SWS), perinatal stroke, and hemispheric cortical dysplasia. In terms of seizure reduction, hemispherectomy remains one of the most successful epilepsy surgery procedures. The modification of this procedure over many years has resulted in lower mortality and morbidity rates. HME might increase morbidity and lower the success rate. Future studies should identify the predictors of outcomes based on the pathology and the type of hemispherectomy. Here, based on a literature review, we discuss the evolution of hemispherectomy techniques and their outcomes and complications.
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| http://dx.doi.org/10.1017/cjn.2020.216 | DOI Listing |
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