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Altered Mental Status and Hyponatremia After 20 Hours of Amiodarone Therapy. | LitMetric

Altered Mental Status and Hyponatremia After 20 Hours of Amiodarone Therapy.

Tex Heart Inst J

Tulane Heart and Vascular Institute, Tulane University School of Medicine, New Orleans, Louisiana 70112.

Published: June 2020

AI Article Synopsis

Article Abstract

A 66-year-old woman with no relevant medical history presented at the emergency department with new-onset atrial fibrillation. We initiated intravenous amiodarone therapy. At 20 hours, the patient experienced severe neurologic symptoms, hyponatremia, and syndrome of inappropriate antidiuretic hormone. We discontinued amiodarone, infused saline solution, and restricted the patient's fluid intake. She recovered in 3 days. This case illustrates that amiodarone-induced syndrome of inappropriate antidiuretic hormone with hyponatremia can occur far earlier than expected during acute amiodarone therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529072PMC
http://dx.doi.org/10.14503/THIJ-18-6849DOI Listing

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