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Objective: Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..
Patients And Methods: Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020.
Direct hemoperfusion with polymyxin B immobilized fiber column (PMX) treatment for acute exacerbation of idiopathic pulmonary fibrosis: A prospective multicenter cohort study.
Respir Investig
December 2024
Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, 6-16-1 Tomioka-Higashi, Kanazawa-ku, Yokohama, Kanagawa, 236-0051, Japan.
Article Synopsis
- - A study investigated the effects of polymyxin B-immobilized fiber column (PMX) treatment on patients with acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF), who typically have a poor prognosis.
- - Results showed a survival rate of 65% at day 28 after PMX treatment, which is significantly higher than the usual 40% survival rate seen with conventional treatments.
- - The study concluded that PMX treatment is safe and potentially improves oxygenation and overall prognosis for AE-IPF patients.
Regenerated carboxymethyl cellulose beads for selective removal of low-density lipoprotein from whole blood.
Carbohydr Polym
January 2025
Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai 200241, PR China. Electronic address:
Low-density lipoprotein (LDL) plays a crucial role in the development of cardiovascular disease. Lowering the level of LDL is an effective therapeutic strategy for treating cardiovascular disease. Here, we developed a facile and robust method to prepare carboxymethyl cellulose beads (CMCBs) for selectively adsorbing LDL.
View Article and Find Full Text PDFInfluence of sequential blood purification therapy on myocardial injury and serum inflammatory cytokine levels in patients with organophosphate poisoning.
Am J Transl Res
October 2024
Department of Emergency, Anxi County Hospital Quanzhou 362400, Fujian, China.
Article Synopsis
- The study aimed to assess the effects of sequential blood purification therapy on heart injury and inflammation in patients with organophosphorus poisoning, comparing two treatment regimens.
- A total of 67 patients were analyzed; one group received conventional treatment with hemoperfusion, while the other received the same plus continuous veno-venous hemofiltration (research group).
- Results showed the research group had better outcomes, including a higher effective treatment rate, quicker recovery times, and lower inflammatory and myocardial injury markers compared to the control group.
Hemoperfusion with CytoSorb in Pediatric Patients: A Monocentric Case Series.
J Clin Med
November 2024
Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Pro- and anti-inflammatory cytokines help regulate the inflammatory response. A cytokine storm is a dysregulated cytokine response associated with sepsis and other conditions that result in a hyper-inflammatory state. Extracorporeal cytokine adsorption has the potential to restore a balanced inflammatory response.
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