GUMBOS (group of uniform materials based on organic salts) is a novel class of materials that exhibits similar features to those of ionic liquids, but have melting points between 25 and 250 °C. GUMBOS can be easily converted into nanomaterials (nanoGUMBOS), with advantages of working at nanoscale. Due to the huge number of possible cation-anion combinations, these materials can be multifunctional and designed for a specific task. This review highlights the possibility of fine-tuning GUMBOS physical and chemical properties in view of changing their ionic counterparts. Their outstanding potential for analytical applications is shown through recent developments in areas such as sensing, and solid-phase extraction. Available methods for synthesis of nanoGUMBOS, and their different outcomes in shapes and optical properties are described, with pros and cons being outlined. Finally, an analysis is made of opportunities and challenges faced by this class of organic ionic materials.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.aca.2020.06.028 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Enhanced extraction of methylene blue by dodecyl-methyl imidazolium dodecyl sulfate GUMBOS - magnetic alginate beads.
Chemosphere
December 2024
Center for Advanced Materials Science (CAMS), Department of Biochemistry, Chemistry, and Physics, Georgia Southern University, Statesboro, GA, 30458, United States. Electronic address:
In this study, dodecyl-methyl imidazolium dodecyl sulfonate ([CMIm][DS]) GUMBOS were synthesized and incorporated into alginate with γ-FeO to fabricate magnetic adsorbent beads ([C₁₂MIm][DS]-beads) for methylene blue (MB) removal. Characterization via ESI-MS, FT-IR, SEM, BET, and TGA confirmed their structure and properties. The beads achieved a maximum adsorption capacity of 4.
View Article and Find Full Text PDFStudies of Protein Binding to Biomimetic Membranes Using a Group of Uniform Materials Based on Organic Salts Derived From 8-Anilino-1-naphthalenesulfonic Acid.
Appl Spectrosc
August 2024
LAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
Tuning the 8-anilino-1-naphthalenesulfonic acid (ANS) structure usually requires harsh conditions and long reaction times, which can result in low yields. Herein, ANS was modified to form an ANS group of uniform materials based on organic salts (GUMBOS), prepared with simple metathesis reactions and distinct cations, namely tetrabutylammonium (N), tetrahexylammonium (N), and tetrabutylphosphonium (P). These ANS-based GUMBOS were investigated as fluorescent probes for membrane binding studies with four proteins having distinct physicochemical properties.
View Article and Find Full Text PDFFluoroquinolone-Based Organic Salts (GUMBOS) with Antibacterial Potential.
Int J Mol Sci
October 2023
LAQV, REQUIMTE, Laboratory of Applied Pharmacy, Department of Chemical Sciences, Faculty of Pharmacy, Porto University, Rua de Jorge Viterbo Ferreira, 4050-313 Porto, Portugal.
Antimicrobial resistance is a silent pandemic considered a public health concern worldwide. Strategic therapies are needed to replace antibacterials that are now ineffective. One approach entails the use of well-known antibacterials along with adjuvants that possess non-antibiotic properties but can extend the lifespan and enhance the effectiveness of the treatment, while also improving the suppression of resistance.
View Article and Find Full Text PDFInfluence of humidity on accuracy of QCM - IR780-based GUMBOS sensor arrays.
Anal Chim Acta
October 2023
Department of Chemistry, Louisiana State University, Baton Rouge, LA, 70803, USA. Electronic address:
Herein, hydrophobic coating materials are reported for QCM detection of VOCs under dry and humid conditions. In this study, IR780-based GUMBOS ([IR780][OTf] and [IR780][NTf2]) were synthesized using an ion exchange reaction and the anions trifluoromethanesulfonimide ([OTf]) and bisperfluoromethanesulfonimide ([NTf2]). The parent iodide salts and GUMBOS ([IR780][I]), [IR780][OTf], and [IR780][NTf2]) were characterized using several analytical techniques.
View Article and Find Full Text PDFImproving the Antimycobacterial Drug Clofazimine through Formation of Organic Salts by Combination with Fluoroquinolones.
Int J Mol Sci
January 2023
LAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, 4169-007 Porto, Portugal.
This work reports the synthesis, structural and thermal analysis, and in vitro evaluation of the antimicrobial activity of two new organic salts (OSs) derived from the antimycobacterial drug clofazimine and the fluoroquinolones ofloxacin or norfloxacin. Organic salts derived from active pharmaceutical ingredients (API-OSs), as those herein disclosed, hold promise as cost-effective formulations with improved features over their parent drugs, thus enabling the mitigation of some of their shortcomings. For instance, in the specific case of clofazimine, its poor solubility severely limits its bioavailability.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!