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Outcomes and predictors of left ventricle recovery in patients with severe left ventricular dysfunction undergoing transcatheter aortic valve implantation.
EuroIntervention
April 2024
Department of Cardiology, Rabin Medical Centre, Petah Tikva, Israel and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background: Data on the likelihood of left ventricle (LV) recovery in patients with severe LV dysfunction and severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI) and its prognostic value are limited.
Aims: We aimed to assess the likelihood of LV recovery following TAVI, examine its association with midterm mortality, and identify independent predictors of LV function.
Methods: In our multicentre registry of 17 TAVI centres in Western Europe and Israel, patients were stratified by baseline LV function (ejection fraction [EF] >/≤30%) and LV response: no LV recovery, LV recovery (EF increase ≥10%), and LV normalisation (EF ≥50% post-TAVI).
Impact of the COVID-19 Pandemic on Global TAVR Activity: The COVID-TAVI Study.
JACC Cardiovasc Interv
February 2024
Department of Cardiology, Galway University Hospital, Galway, Ireland; School of Medicine, University of Galway, Galway, Ireland. Electronic address:
Article Synopsis
- The COVID-19 pandemic led to significant treatment delays for patients needing transcatheter aortic valve replacement (TAVR), with a marked decrease in procedure volumes during the first two waves of the pandemic.
- The study analyzed TAVR case data from 130 centers in 61 countries, finding a 15% drop in cases during the first wave and 7% in the second, particularly affecting regions like Africa, Central-South America, and Asia.
- Factors such as hospital type (private vs public), urban vs rural location, low procedure volumes, a country's socioeconomic status, and stringent public health measures contributed to these reductions, highlighting the need for improved public health policies for future health crises.
In-hospital outcomes after PCI and TAVI versus combined aortic valve replacement and coronary surgery. Response.
Rev Esp Cardiol (Engl Ed)
October 2023
Fundación Instituto para la Mejora de la Asistencia Sanitaria, Madrid, Spain.
Impact of a pulmonary embolism response team initiative on hospital mortality of patients with bilateral pulmonary embolism.
Med Clin (Barc)
June 2023
Cardiovascular Institute, Hospital Universitario Clínico San Carlos, Madrid,Spain. Electronic address:
Introduction: Pulmonary embolism (PE) response teams (PERT) for the management of high-risk PE (HR-PE) and intermediate-high risk PE (IHR-PE) are encouraged in PE guidelines. We aimed to assess the impact of a PERT initiative on mortality in these groups of patients, compared with standard care.
Methods: We conducted a prospective, single-center registry, including consecutive patients with HR-PE and IHR-PE with PERT activation from February-2018 to December-2020 (PERT group, n=78 patients) and compared it with an historic cohort of patients admitted to our hospital in a previous 2-year period (2014-2016), managed with standard of care (SC-group, n=108 patients).
Vascular healing responses to paclitaxel coated balloons or everolimus eluting stents for the treatment of in-stent restenosis. Insights from optical coherence tomography.
Coron Artery Dis
December 2022
Departamento de Cardiología Intervencionista, Hospital Universitario Clínico San Carlos, IdISSC, Universidad Complutense.
Article Synopsis
- Treatment of in-stent restenosis (ISR) is challenging, with limited data on vascular healing after using paclitaxel-coated balloons (PCB) versus everolimus-eluting stents (EES).
- In a study of 64 patients, both treatments showed similar baseline characteristics, but follow-up revealed that EES had a larger mean lumen area compared to PCB, despite no difference in angiographic restenosis rates.
- PCB-treated ISR demonstrated greater strut coverage and a tendency towards healthier tissue structure compared to EES, indicating benefits in vascular healing with PCB.
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