Introduction: Lung cancer is the leading cause of cancer-related mortality worldwide. Although lung cancer is predominantly observed in smokers, non-smoking patients account for 20% of cases worldwide. In this article, we present a case of lung adenocarcinoma that originated from a postoperative scar. We present a 62-year-old male patient who, while being studied for Paget's disease of bone, presented a 1.5 cm pulmonary nodule (SUV 1.6) as an imaging finding in the posterior segment of the left lung. He underwent a upper left lung segmentectomy.
Results: During the routine follow-up of his underlying disease, 12 years after the original surgery, a pulmonary nodule was found. The particularity of the sample is based on the macroscopic observation of the tumor piece where the development of the neoplastic mass on the mechanical suture of the previous surgery performed 12 years ago is shown.
Conclusion: We describe a rare cancer development mechanism in clinical practice, from chronic postoperative inflammation due to mechanical suturing.
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http://dx.doi.org/10.31053/1853.0605.v77.n3.29294 | DOI Listing |
Curr Med Chem
January 2025
Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Mahesana, Gujarat, 384012, India.
Therapeutic hurdles persist in the fight against lung cancer, although it is a leading cause of cancer-related deaths worldwide. Results are still not up to par, even with the best efforts of conventional medicine, thus new avenues of investigation are required. Examining how immunotherapy, precision medicine, and AI are being used to manage lung cancer, this review shows how these tools can change the game for patients and increase their chances of survival.
View Article and Find Full Text PDFBiomed Res Int
January 2025
Center for Personalized Nanomedicine, Australian Institute for Bioengineering & Nanotechnology (AIBN), The University of Queensland, Brisbane, Queensland, Australia.
Environmental pollution has been a significant concern for the last few years. The leather industry significantly contributes to the economy but is one of Bangladesh's most prominent polluting industries. It is also responsible for several severe diseases such as cancer, lung diseases, and heart diseases of leather workers because they use bleaching agents and chemicals, and these have numerous adverse effects on human health.
View Article and Find Full Text PDFJACC Adv
December 2024
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, New York, USA.
Background: The Hispanic/Latino population is not uniform. Prevalence and clinical outcomes of cardiac arrhythmias in ethnic background subgroups are variable, but the reasons for differences are unclear. Vectorcardiographic Global Electrical Heterogeneity (GEH) has been shown to be associated with adverse cardiovascular outcomes.
View Article and Find Full Text PDFLaryngoscope Investig Otolaryngol
February 2025
Department of Otolaryngology, Head and Neck Surgery The Affiliated Hospital of Qingdao University Qingdao China.
Introduction: Systemic inflammatory and nutritional markers are associated with the prognosis of various cancers. However, their association with sinonasal squamous cell carcinoma (SNSCC) prognosis remains unclear. This study aimed to identify systemic inflammatory and nutritional markers associated with the postoperative prognosis of patients with SNSCC and to clarify the clinical value of these markers.
View Article and Find Full Text PDFTheranostics
January 2025
Department of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China.
Colorectal cancer (CRC) is a leading cause of cancer-related mortality. Epigenetic modifications play a significant role in the progression of CRC. KAT7, a histone acetyltransferase, has an unclear role in CRC.
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