Hot snare polypectomy versus endoscopic mucosal resection for small colorectal polyps: a randomized controlled trial.

Surg Endosc

Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.

Published: September 2021

AI Article Synopsis

  • This study compared endoscopic mucosal resection (EMR) and hot snare polypectomy (HSP) for removing small colorectal polyps (5-10 mm) to see which method had better complete resection rates and fewer adverse events.
  • The results showed that while both methods had similar complete resection rates (around 96% for HSP and 95% for EMR), the R0 resection rate, indicating no cancerous tissue at the margins, was significantly higher for EMR (74.8%) compared to HSP (49.7%).
  • Both techniques had no significant difference in adverse event rates, suggesting safety in using either method for small polyps.

Article Abstract

Background And Aims: This study was performed to compare endoscopic mucosal resection (EMR) with hot snare polypectomy (HSP) in terms of the complete resection rate and the incidence of adverse events for resecting small (5-10 mm) colorectal polyps.

Methods: Small colorectal polyps (5-10 mm) with neoplastic features were randomly allocated to either the HSP or EMR group. A submucosal injection was performed prior to hot snaring in the EMR group only. Complete resection was defined as the absence of neoplastic tissue from two additional biopsies of the polypectomy site. R0 resection was defined as the absence of neoplastic tissue at the margin of the resected specimen.

Results: A total of 362 colon polyps from 272 patients were included, and 167 polyps in the HSP group and 155 polyps in the EMR group were analyzed. Between the polypectomy techniques, there was no significant difference in the complete resection rates, which were 96.4% (161/167) in the HSP group and 95.5% (148/155) in the EMR group (P = 0.67). The R0 resection rate in the HSP and EMR groups was significantly different, with 49.7% (83/167) and 74.8% (116/155), respectively (P < 0.001). There was no significant difference in the incidence of adverse events between the two groups.

Conclusions: The complete resection rates for small (5-10 mm) polyps were not different between HSP and EMR.

Trial Registry: ClincialTrials.gov number NCT02239536.

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Source
http://dx.doi.org/10.1007/s00464-020-07994-7DOI Listing

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