Purpose: The fusion of the upper cervical spine in children is demanding due to its reduced size, its anatomical complexity, or a severe pathology of the cranio-cervical junction. In some pediatric patients with today's more popular C1-C2 or, occipito-C2 techniques, it is impossible, or very risky to perform a short upper cervical fixation.

Methods: We present the utility and good results of ipsilateral laminar C2 screws insertion technique in two pediatric cases with low C2 laminar profile. Case 1: a 5-year-old child with a C1-C2 unstable subluxation, and a condylar assimilation of C1, where we performed an occipito-C2 fixation using an occipital plate and this modified translaminar C2 screw technique. Case 2: a 8-year-old Down syndrome boy who suffered an unstable subluxation of C1-C2 upon whom we performed a C1-C2 screw fixation using the same technique.

Results: Both cases have been followed up over a period of 7 and 2 years respectively, with good clinical results.

Conclusions: We describe the technique and the feasibility of the ipsilateral insertion of translaminar C2 screws in children with low laminar profiles, as a good alternative to other techniques when the anatomy of the C2 does not permit its use or make them very risky.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00381-020-04899-7DOI Listing

Publication Analysis

Top Keywords

low laminar
12
translaminar screws
8
screws insertion
8
children low
8
laminar profile
8
upper cervical
8
unstable subluxation
8
ipsilateral translaminar
4
insertion cervical
4
cervical fixation
4

Similar Publications

Cyto-, gene, and multireceptor architecture of the early postnatal mouse hippocampal complex.

Prog Neurobiol

December 2024

Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, 52425 Jülich, Germany; C. & O. Vogt Institute for Brain Research, Heinrich-Heine-University, 40225 Dusseldorf, Germany.

Neurotransmitter receptors are key molecules in signal transmission in the adult brain, and their precise spatial and temporal balance expressions also play a critical role in normal brain development. However, the specific balance expression of multiple receptors during hippocampal development is not well characterized. In this study, we used quantitative in vivo receptor autoradiography to measure the distributions and densities of 18 neurotransmitter receptor types in the mouse hippocampal complex at postnatal day 7, and compared them with the expressions of their corresponding encoding genes.

View Article and Find Full Text PDF

A versatile and automatic on-line screening method: Transverse diffusion of laminar flow profiles-based capillary electrophoresis for exploring PTP1B inhibitors in natural products.

J Chromatogr A

December 2024

KU Leuven - University of Leuven, Pharmaceutical Analysis, Department of Pharmaceutical and Pharmacological Sciences, O&N2, PB 923, Herestraat 49 3000 Leuven, Belgium. Electronic address:

Natural products (NPs) play an important role in drug discovery and drug development due to their diverse chemical properties and biological activities. In the present work, an on-line capillary electrophoresis (CE) method was developed and applied to screen protein tyrosine phosphatase 1B (PTP1B) inhibitors in NPs. As a generic technique, transverse diffusion of laminar flow profiles (TDLFP) was utilized to mix all reactants in the capillary for on-line enzymatic reaction.

View Article and Find Full Text PDF

Spall: accurate and robust unveiling cellular landscapes from spatially resolved transcriptomics data using a decomposition network.

BMC Bioinformatics

December 2024

Center of Intelligent Medicine, School of Control Science and Engineering, Shandong University, Jinan, 250061, Shandong, China.

Recent developments in spatially resolved transcriptomics (SRT) enable the characterization of spatial structures for different tissues. Many decomposition methods have been proposed to depict the cellular distribution within tissues. However, existing computational methods struggle to balance spatial continuity in cell distribution with the preservation of cell-specific characteristics.

View Article and Find Full Text PDF

Intermittent switchings between weakly chaotic (laminar) and strongly chaotic (bursty) states are often observed in systems with high-dimensional chaotic attractors, such as fluid turbulence. They differ from the intermittency of a low-dimensional system accompanied by the stability change of a fixed point or a periodic orbit in that the intermittency of a high-dimensional system tends to appear in a wide range of parameters. This paper considers a case where the skeleton of a laminar state L exists as a proper chaotic subset S of a chaotic attractor X, that is, S⊊X.

View Article and Find Full Text PDF

Reusable EWOD-based microfluidic system for active droplet generation.

Lab Chip

December 2024

Department of Nanoscience and Engineering, Center for Nano Manufacturing, Inje University, Gimhae, 50834, Republic of Korea.

Droplets are essential in a wide range of microfluidic applications, but traditional passive droplet generation methods suffer from slow response speed and the need for precise flow rate adjustment. Here, we present an active droplet generation method through electrowetting-on-dielectric (EWOD). Electrowetting is a technique that uses an electric field to change the wettability of a surface.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!