Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
From Lab to Limb: Unraveling Translational Insights and Significance of Animal Models in Lower Extremity Transplantation.
JPRAS Open
March 2025
Department of Surgery, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.
The advancements in medicine throughout the twentieth century have been largely attributed to animal studies. The initial step in researching an animal disease is to establish a model closely resembling the clinical circumstances in humans. Consequently, an excellent animal model is essential for almost any experimental research.
View Article and Find Full Text PDFExperimental Models in Penile Transplantation: Translational Insights and Relevance to Clinical Application.
Cureus
November 2024
Department of Surgery, Wake Forest School of Medicine, Winston-Salem, USA.
Animal research is an essential contributor to the medical achievements of the last century. The first step of studying a disease in animals is the development of a model which is relevant to the clinical situation in humans. Thus, a good animal model is the sine qua non of the experimental research.
View Article and Find Full Text PDFA high concentration of neutrophil extracellular traps is observed in humans and mice suffering from endometriosis.
J Reprod Immunol
December 2024
Department of Gynaecology and Obstetrics, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, PR China. Electronic address:
We wished to ascertain if there is an association between neutrophil extracellular traps and endometriosis (EMS). We collected the lesional tissues and normal endometrium of 30 patients suffering from endometriosis. Samples were also taken from healthy controls.
View Article and Find Full Text PDFLymph Node Inclusion in a Modified Osteomyocutaneous Allograft for Vascularized Composite Allotransplantation: Establishment and Feasibility Assessment in a Pig Model.
Plast Reconstr Surg Glob Open
November 2024
From the Department of Plastic and Hand Surgery, Inselspital University Hospital, University of Bern, Bern, Switzerland.
Article Synopsis
- Researchers aimed to improve a porcine model used for vascularized composite allotransplantation (VCA) by reducing its bulk and including critical vascularized lymph nodes.
- The study involved harvesting and analyzing porcine flaps using both conventional and modified techniques, with results showing a significant reduction in flap weight and muscle/bone ratio in the modified group.
- The findings indicate that the modified model maintains vascularization while providing a more suitable platform for studying immunological responses in transplant research, suggesting its potential for broader experimental applications.
Vascular changes in vascularized composite allotransplantation.
Curr Opin Organ Transplant
December 2024
Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.
Purpose Of Review: Allograft vasculopathy in vascularized composite allografts (VCA) remains understudied. This review explores the vascular changes in VCA, focused on recent literature.
Recent Findings: Allograft vasculopathy in VCA generally includes progressive concentric myointimal thickening and luminal narrowing of arterial vessels through endothelial deterioration and proliferation of smooth muscle cells.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!