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Healing by secondary intention over NeoDura applicated on a craniectomy defect: a case report and literature review.
J Med Case Rep
December 2024
UZ Leuven, Plastic, Reconstructive and Aesthetic Surgery, Herestraat 49, 3000, Louvain, Belgium.
Background: NeoDura (Medprin Biotech Gmbh) is an absorbable dural repair patch consisting of degradable poly-L-lactic acid and porcine gelatin that provides a hermetic closure of the dura mater (Medprin Biotech. Neodura. Dural Repair Patch [Brochure].
View Article and Find Full Text PDFAnalytical microscopy techniques using coaxial and oblique illuminations to detect thin glass particulates generated from glass vials for parenteral drug products.
Appl Microsc
October 2024
Analytical Development and Operations, Gilead Sciences Inc, Foster City, CA, 94404, USA.
Glass vials are the most widely used primary containers for the packaging of parenteral products due to their optical clarity, general inertness, and hermetic properties, but under certain circumstances, they can pose safety concerns. Most of these issues are related to the potential formation of glass particulates through delamination or precipitation, resulting from the chemical interaction between the drug product and the inner surface of the glass vial. Hence, it is imperative for pharmaceutical companies to conduct product-vial compatibility studies to determine the appropriate packaging/container closure system.
View Article and Find Full Text PDFEnhancing wine shelf-life: Insights into factors influencing oxidation and preservation.
Heliyon
August 2024
Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124, Pisa, Italy.
Background: Understanding the shelf life of wine is complex and involves factors such as aroma preservation, flavour development and market acceptance. Ageing potential, crucial for flavour complexity, exposes wine to oxidation, influenced by oxygen, temperature and light, with an impact on quality. This type of oxidation is non-enzymatic, is catalyzed by metal ions and alters colour and flavour.
View Article and Find Full Text PDFCollagen Membrane as Artificial Dura Substitute: A Comprehensive In Vivo Study of Efficiency and Substitution Compared to Durepair.
World Neurosurg
October 2024
Department of Pediatric Surgery, Moscow Regional Scientific Research Clinical Institute M.F. Vladimirsky, Moscow, Russia.
Background And Objectives: The dura mater is a barrier between the brain and the surrounding environment. Injuries to the dura can lead to serious complications, therefore, ensuring a hermetic closure of the dura is a primary task for a neurosurgeon. The aim of the study is to compare the effectiveness of applying the newly developed ViscollDURA collagen membrane (VDCM), with the commercially available Durepair (xenogeneic collagen) in animal model.
View Article and Find Full Text PDFDural Closure Training With Prototyped Model.
Cureus
June 2024
Medicine, Positivo University, Curitiba, BRA.
Introduction: The hermetic closure of the dura mater is a critical step in neurosurgical training, often undervalued but crucial to preventing serious complications such as cerebrospinal fluid (CSF) leaks leading to meningitis and death. Inadequate closure, often due to insufficient training, can result in challenging complications, including prolonged hospitalization and reoperation.
Objective: To address the deficiencies in dural closure training, this study aims to describe a 3D prototype for simulating post-craniotomy dura mater suturing.
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