In the wake of the control of light at the sub-wavelength scale by nanoresonators, metasurfaces allowing strong field exaltations are an attractive platform to enhance nonlinear processes. Recently, high efficiency second harmonic and difference frequency generations were demonstrated in metasurfaces that generate a nonlinear polarization normal to the surface. Here, we introduce a mode matched resonator that is able to produce this particular nonlinear polarization in a layer of gallium arsenide associated with a gold metasurface. The nonlinear conversion mechanism is described as a two-step process in which efficiency is shown to yield a good colocalization and a strong enhancement of the pump fields, as well as a high extraction efficiency of the generated field. This mode-matched metasurface is able to reach a difference frequency generation (DFG) efficiency of 10W/W. This opens a new paradigm where alternative nonlinear materials could be reintroduced in metasurfaces and yields even higher efficiency than high effective χ structures.
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http://dx.doi.org/10.1364/OE.398733 | DOI Listing |
Pacing Clin Electrophysiol
December 2024
Arrhythmia Unit, Department of Cardiology, Hospital Juan Ramón Jiménez, Huelva, Spain.
Background: Interventricular dyssynchrony derived from the classic non-physiological stimulation (n-PS) of the right ventricle (RV) is a known cause of left ventricular dysfunction (LVDys).
Methods: This was a prospective descriptive single-center study. We analyzed patients who develop LVDys with n-PS, and the results after upgrading to conduction system pacing (CSP).
J Med Ultrason (2001)
December 2024
Department of Internal Medicine, Kuma Hospital, Kobe, Hyogo, 650-0011, Japan.
Purpose: Parathyroid lipoadenomas are difficult to recognize preoperatively; hence, they may remain undetected. Difficulty in recognition is thought to be due to the adipocytes present in the tumor. This study aimed to clarify the impact of adipocytes as a component of parathyroid adenomas on ultrasound evaluation.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Medicine, Office of Medical Education Research and Development, College of Human Medicine, Michigan State University, East Lansing, MI, USA.
Purpose: This study quantified the impact of clinical clerkships on medical students' disciplinary knowledge using the Comprehensive Clinical Science Examination (CCSE) as a formative assessment tool.
Methods: This study involved 155 third-year medical students in the College of Human Medicine at Michigan State University who matriculated in 2016. Disciplinary scores on their individual Comprehensive Clinical Science Examination reports were extracted by digitizing the bar charts using image processing techniques.
Ann Hematol
December 2024
Department of Medical Oncology, Hebei Key Laboratory of Cancer Radiotherapy and Chemotherapy, Affiliated Hospital of Hebei University, 212 Yuhua East Road, Baoding, 071000, Hebei, China.
The first-line treatment for chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has recently undergone major changes, and targeted therapies have ushered in a new era of CLL/SLL treatment. Scientists in different countries have successively analyzed the efficacy of various drugs, but safety studies are relatively insufficient. Therefore, this systematic evaluation and retrospective meta-analysis was conducted to compare the differences in adverse effects and their incidence among first-line treatment regimens for CLL/SLL.
View Article and Find Full Text PDFCancer Rep (Hoboken)
December 2024
Department of Urology, Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, Brandenburg an der Havel, Germany.
Background: Despite constant improvements, incontinence is one of the most relevant and quality-of-life-reducing side effects of radical prostatectomy (RP) and, in addition to patient-specific factors such as age, the experience of the surgeon/center and the surgical technique used play an important role.
Aims: To present current real-world data on short-term incontinence after RP from one of the largest German rehabilitation centers in 2022 and to compare it to the results from the same institution in 2016.
Methods And Results: Retrospective, unicentric, univariate analysis of data from 1394 men after RP in 2022 on admission and discharge from the rehabilitation clinic.
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