AI Article Synopsis
- Antimicrobial photodynamic therapy (A-PDT) is an adjunctive method to enhance root canal disinfection by targeting intracanal biofilm.
- A systematic review included 27 studies that were analyzed for the effectiveness of PDT when combined with traditional endodontic procedures.
- While PDT generally decreased bacterial viability in most studies, the lack of precise quantification and biases in the research limited the robustness of the conclusions.
Article Abstract
Background: Antimicrobial photodynamic therapy (A-PDT), is one of the adjunctive therapies developed to improve the effectiveness of root canal disinfection.. The aim of this study was to analyze the antimicrobial effect of PDT on intracanal biofilm.
Methods: Two reviewers conducted a literature search in PubMed, MEDLINE, Lilacs, SciELO, EMBASE and Google Scholar using the following search strategy: photochemotherapy "[Mesh] OR (photodynamic therapy) AND" dental plaque "[Mesh] OR (dental biofilm) AND (root canal). The following data were collected: publication year, author's name, study site, type of study, participant number, type of photosensitizer, type of laser, method of data collection, application time and results. Study quality was assessed using the Methodological Index for Non-Randomized Studies (MINORS).
Results: After selection based on title, abstract and full text, 27 studies were included in this systematic review. PDT reduced bacterial viability in most studies when combined with conventional endodontic techniques.
Conclusion: PDT reduced bacterial counts in most studies, especially when used as an adjunct to the conventional endodontic technique to treat refractory infection. However, PDT effects on in vitro bacterial biofilm were not accurately quantified because of the numerous biases in the studies reviewed.
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| http://dx.doi.org/10.1016/j.pdpdt.2020.102025 | DOI Listing |
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