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Exploring the effect of hsa-miR-19b-3p on IL-1R1 expression and serum levels in alopecia areata.
Arch Dermatol Res
January 2025
Department of Dermatology, Venereology, and Sexology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Alopecia areata (AA) is an autoimmune condition marked by hair loss, linked to inflammatory processes involving the interleukin-1 receptor type 1 (IL-1R1) pathway. This study aims to explore the relationship between IL-1R1 gene expression, serum IL-1R1 levels, and hsa-miR-19b-3p in relation to AA severity. Using a case-control design, we assessed 100 AA patients and 100 healthy controls, measuring serum IL-1R1 through enzyme-linked immunosorbent assay (ELISA) and analyzing IL-1R1 gene and hsa-miR-19b-3p expression levels via quantitative real-time PCR (qRT-PCR).
View Article and Find Full Text PDFDevelopment and validation of the Information Literacy Measurement Scale (ILMS-34) in Chinese public health practitioners.
BMC Med Educ
January 2025
School of Health Management, Southern Medical University, Guangzhou, 510515, China.
Background: Public health professionals (PHPs) have increasing information needs to inform evidence-based public health decisions and practice, which requires good information literacy. A comprehensive and reliable assessment tool is necessary to assess PHPs' literacy and guide future promotion programs. However, there is a lack of measurement tools specifically for the information literacy of PHPs.
View Article and Find Full Text PDFTicks jump in a warmer world: Global distribution shifts of main pathogenic ticks are associated with future climate change.
J Environ Manage
January 2025
College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
In recent decades, the threats of ticks and tick-borne diseases (TBDs) increased extensively with environmental change, urbanization, and rapidly changing interactions between human and animals. However, large-scale distribution of tick and TBD risks as well as their relationship with environmental change remain inadequately unclear. Here, we first proposed a "tick-pathogen-habitat-human" model to project the global potential distribution of main pathogenic ticks using a total of 70,714 occurrence records.
View Article and Find Full Text PDFKnowledge of the risks of ultraviolet radiation, sun exposure attitudes and practices among Lebanese university students.
Prev Med Rep
November 2024
Higher Institute of Public Health, Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
Background: Exposure to Ultraviolet radiation (UVR) is a major risk factor for skin cancer. Data about UVR risk knowledge and exposure behaviors in the Lebanese population are scarce.
Aim: To evaluate the association between UVR risks knowledge, attitudes, and behaviors among Lebanese university students in the aim of promoting primary prevention of skin cancer.
Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review.
Front Pharmacol
January 2025
Department of Dermatology, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Total glucosides of paeony (TGP) are a group of monoterpenes extracted from , primarily including metabolites such as paeoniflorin and oxypaeoniflorin. Modern pharmacological studies have shown that TGP possesses a variety of biological effects, including immunomodulatory, anti-inflammatory, hepatoprotective, nephroprotective, antidepressant, and cell proliferation regulatory activities. In recent years, clinical research has demonstrated favorable therapeutic effects of TGP on disorders of the liver, cardiovascular, nervous, endocrine, and skeletal systems.
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