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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered virus for which remdesivir is the only antiviral available. We report the occurrence of a mutation in RdRP (D484Y) following treatment with remdesivir in a 76-year-old female with post-rituximab B-cell immunodeficiency and persistent SARS-CoV-2 viremia. A cure was achieved after supplementation with convalescent plasma.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543308 | PMC |
| http://dx.doi.org/10.1093/cid/ciaa1474 | DOI Listing |
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