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Disease-wide association study uncovers disease continuum network of unipolar depression.
Eur Neuropsychopharmacol
December 2024
Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Academy of Military Medical Sciences, 27 Taiping Road, Beijing 100850, China. Electronic address:
Unipolar depression is typically regarded as a psychiatric disorder, yet it frequently coexists with various major diseases. This study employs a Disease-Wide Association Study (DWAS) approach to map the disease continuum surrounding unipolar depression, analyzing data from a registry cohort of 392,423 individuals, including 43,280 diagnosed cases of unipolar depression. Significant associations were identified between depression and comorbidities across multiple organ systems, including both mental and physical disorders.
View Article and Find Full Text PDFThe best stress ulcer prophylaxis in burn patients: The gap between research and practice.
Burns
December 2024
Department of Clinical Pharmacy, School of Pharmacy, Shahid Sadoughi University of Medical Science, Yazd, Iran. Electronic address:
Reply to Huang et al.
Gastroenterology
December 2024
Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California; G. Oppenheimer Center for Neurobiology of Stress and Resilience, Los Angeles, California; UCLA Goodman-Luskin Microbiome Center, Los Angeles, California; University of California, Los Angeles, Los Angeles, California. Electronic address:
The Benefits of Virtual Reality Travel on Symptom Burden and Mental Health of Hemodialysis Patients.
J Pain Symptom Manage
December 2024
The First Affiliated Hospital of Xinxiang Medical University, Xinxiang City, 453100, China.
Background: . Hemodialysis (HD) patients often face a heavy symptom burden, low subjective well-being, and high perceived stress. Traditional non-pharmacological interventions have limited effectiveness in improving this situation.
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