Intravenous immunoglobulin (IVIG) is used in the treatment of a variety of autoimmune neurological disorders and is generally regarded as safe. We present a case series where IVIG causes transaminitis. The adverse effects are mostly due to the stabilizing agent used to prepare the IVIG (e.g., maltose in this series). While the adverse effects are usually self-limiting, physicians should be cautious in administering an IVIG preparation to these patients.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515744PMC
http://dx.doi.org/10.7759/cureus.10020DOI Listing

Publication Analysis

Top Keywords

case series
8
adverse effects
8
intravenous immunoglobulin-associated
4
immunoglobulin-associated elevation
4
elevation liver
4
liver enzymes
4
enzymes neurological
4
neurological autoimmune
4
autoimmune disorder
4
disorder case
4

Similar Publications

Novel Meningoencephalomyelitis Associated With Vimentin IgG Autoantibodies.

JAMA Neurol

January 2025

Department of Neurology, Xuanwu Hospital Capital Medical University, National Center for Neurological Disorders, Beijing, China.

Importance: Autoantibodies targeting astrocytes, such as those against glial fibrillary acidic protein (GFAP) or aquaporin protein 4, are crucial diagnostic markers for autoimmune astrocytopathy among central nervous system (CNS) autoimmune disorders. However, diagnosis remains challenging for patients lacking specific autoantibodies.

Objective: To characterize a syndrome of unknown meningoencephalomyelitis associated with an astrocytic autoantibody.

View Article and Find Full Text PDF

Azo dye was used to prepare a new series of complexes with chlorides of rhodium (Rh), ruthenium (Ru), and corona (Au). The prepared materials were subjected to infrared, ultraviolet-visible, and mass spectrometry, as well as thermogravimetric analysis, differential calorimetry, and elemental analysis. Conductivity, magnetic susceptibility, metal content, and chlorine content of the complexes were also measured.

View Article and Find Full Text PDF

Effectiveness of Isotretinoin Administration in Rhinoplasty: A Systematic Review.

Facial Plast Surg Aesthet Med

January 2025

Division of Facial Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.

To investigate the effectiveness of isotretinoin use in patients with thick nasal skin to improve rhinoplasty outcomes. The Population Intervention Comparison Outcome framework was utilized for selecting relevant studies for review. The databases of Medline, Embase, Cinahl, Central, Scopus, and Web of Science were searched in June 2024.

View Article and Find Full Text PDF

Objective: To report clinical outcomes of skeletally immature dogs with antebrachial deformities secondary to premature closure of the distal radial physis (PCDRP) treated with angular corrections and distraction osteogenesis using circular external skeletal fixation (CESF).

Study Design: Retrospective multi-institutional case series.

Animals: A total of 12 client-owned dogs with premature distal radial physeal closure.

View Article and Find Full Text PDF

Introduction: Obstructive sleep apnoea (OSA) in children is associated with numerous adverse outcomes, including elevated blood pressure. While the associations between OSA, obesity, and autonomic dysfunction are recognised, the precise mechanisms linking these factors and their relationship with elevated blood pressure in children remain unclear.

Methods: This retrospective case series included 76 children with OSA.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!