Simulation of large scale biologically plausible spiking neural networks, e.g., Bayesian Confidence Propagation Neural Network (BCPNN), usually requires high-performance supercomputers with dedicated accelerators, such as GPUs, FPGAs, or even Application-Specific Integrated Circuits (ASICs). Almost all of these computers are based on the von Neumann architecture that separates storage and computation. In all these solutions, memory access is the dominant cost even for highly customized computation and memory architecture, such as ASICs. In this paper, we propose an optimization technique that can make the BCPNN simulation memory access friendly by avoiding a dual-access pattern. The BCPNN synaptic traces and weights are organized as matrices accessed both row-wise and column-wise. Accessing data stored in DRAM with a dual-access pattern is extremely expensive. A post-synaptic history buffer and an approximation function thus are introduced to eliminate the troublesome column update. The error analysis combining theoretical analysis and experiments suggests that the probability of introducing intolerable errors by such optimization can be bounded to a very small number, which makes it almost negligible. Derivation and validation of such a bound is the core contribution of this paper. Experiments on a GPU platform shows that compared to the previously reported baseline simulation strategy, the proposed optimization technique reduces the storage requirement by 33%, the global memory access demand by more than 27% and DRAM access rate by more than 5%; the latency of updating synaptic traces decreases by roughly 50%. Compared with the other similar optimization technique reported in the literature, our method clearly shows considerably better results. Although the BCPNN is used as the targeted neural network model, the proposed optimization method can be applied to other artificial neural network models based on a Hebbian learning rule.
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http://dx.doi.org/10.3389/fnins.2020.00878 | DOI Listing |
Nat Mater
January 2025
Department of Electronic and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong, China.
Machine learning algorithms have proven to be effective for essential quantum computation tasks such as quantum error correction and quantum control. Efficient hardware implementation of these algorithms at cryogenic temperatures is essential. Here we utilize magnetic topological insulators as memristors (termed magnetic topological memristors) and introduce a cryogenic in-memory computing scheme based on the coexistence of a chiral edge state and a topological surface state.
View Article and Find Full Text PDFPsychol Sci
January 2025
Department of Psychology, University of Massachusetts Boston.
Most work on working memory development has children remember a set of items as well as they can. However, this approach sidesteps the , the integration of external information with memory. Indeed, adults prefer to use external resources (e.
View Article and Find Full Text PDFWe have previously identified that infection induces a unique form of myeloid training that protects male but not female mice from high fat diet induced disease. Here we demonstrate that ovarian derived hormones account for this sex specific difference. Ovariectomy of females prior to infection permits metabolic reprogramming of the myeloid lineage, with BMDM exhibiting carbon source flexibility for cellular respiration, and mice protected from systemic metabolic disease.
View Article and Find Full Text PDFCureus
December 2024
Psychiatry, Dr. Kamal Psychiatric Hospital, Bethlehem, PSE.
Dissociation is a cognitive process that disrupts consciousness, identity, or memory. It is frequently used as a form of defense in response to significant stress or trauma. In serious situations, it might show as a dissociative disorder, which extremely impairs psychological functioning.
View Article and Find Full Text PDFJ Alzheimers Dis
January 2025
Aging Brain and Memory Clinic, Department of Neuroscience "Rita Levi-Montalcini", University of Torino, Torino, Italy.
This study evaluated the diagnostic performance of plasma biomarkers for Alzheimer's disease (AD) using an automated platform. In a cohort of 74 consecutive patients, plasma p-Tau181 levels were significantly higher in AD compared to non-AD groups and showed correlation with cerebrospinal fluid biomarkers. Plasma p-Tau181 demonstrated high diagnostic accuracy for AD, with an area under the curve of 0.
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