Objective: Colposcopy is a direct microscopic method and is the gold standard tool to detect early cervical dysplastic lesions. In the past, many attempts have been made to use gynecologic methods to examine the oral mucosa. The aim of this study was to detect the diagnostic accuracy of oral colposcopy in diagnosing oral dysplastic lesions in comparison with microscopic evaluation based on biopsy and compare Reid's Colposcopic Index (RCI) and the Swede scoring system in diagnosing oral dysplastic lesions.
Study Design: Twenty-five patients who presented for diagnosis of oral leukoplakia to the Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University (Cairo, Egypt) and met the selection criteria were recruited in this study. Each patient was subjected to colposcopic examination, followed by biopsy to confirm the results of colposcopy. The sensitivity and specificity of oral colposcopy were calculated after colposcopic assessment by using the Swede scoring system and the RCI.
Results: The diagnostic accuracy of oral colposcopy with use of the Swede scoring system was superior to that of oral colposcopy with the use of the RCI.
Conclusions: Colposcopic examination using the Swede scoring system is very specific for diagnosing oral epithelial dysplasia and for using the "see-and-treat" method, whereas the RCI is a very sensitive screening method for the diagnosis of oral epithelial dysplasia in oral potentially malignant disorders.
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http://dx.doi.org/10.1016/j.oooo.2020.08.019 | DOI Listing |
Comput Biol Med
January 2025
Institute of the Cervix, Paris, France. Electronic address:
Background: The current cervical cancer screening and diagnosis have limitations due to their subjectivity and lack of reproducibility. We describe the development of a deep learning (DL)-based diagnostic risk prediction model and evaluate its potential for clinical impact.
Method: We developed and internally validated a DL model which accommodates both clinical data and colposcopy images in predicting the patients CIN2+ status using a retrospective cohort of 6356 cases of LEEP-conization/cone-biopsy (gold-standard diagnosis) following an abnormal screening result.
Cancers (Basel)
October 2024
Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
: This study aimed to evaluate psychosocial burden and its associated factors in women who were referred for additional diagnostic procedures following receipt of a positive cervical-cancer-screening smear result. : A cross-sectional study was performed in a consecutive cohort of only women who received an abnormal Papanicolaou screening result and therefore presented to a gynecologist for additional diagnostic examinations (colposcopy/biopsy/endocervical curettage) at the Clinic for Gynecology and Obstetrics of the Clinical Center. Multivariate linear regression was used for data analysis, with Bonferroni correction applied for multiple comparisons.
View Article and Find Full Text PDFCancers (Basel)
September 2024
Department of Conservative Dentistry with Endodontics, Medical University of Lublin, ul. Chodźki 6, 20-093 Lublin, Poland.
J Cancer Res Clin Oncol
September 2024
Center for Familial Breast and Ovarian Cancer and Center for Integrated Oncology, Medical Faculty, University Hospital Cologne, Cologne, Germany.
Purpose: To support doctors in counselling women with genetic predisposition for breast or gynecologic cancers on endocrine interventions.
Methods: Evidence on the safety of endocrine interventions for fertility treatment, contraception, hormone replacement therapy after risk-reducing salpingo-oophorectomy (RRSO) or treatment of symptoms during peri- and postmenopause was analysed for carriers of probably pathogenic and pathogenic variants in BRCA1 or BRCA2 (BRCA1/2-pV), in other breast and ovarian cancer genes and the Lynch Syndrome. Cancer risks were compared with data on risks for the general population.
BMC Womens Health
June 2024
Department of Gynecological Oncology, Antalya Health Science University Training and Research Hospital, Varlik m., Kazım Karabekir street, Antalya, 07100, Turkey.
Background: This study aimed to evaluate the outcomes of patients diagnosed with stage IB2/IIA2 cervical squamous cell carcinoma who underwent neoadjuvant chemotherapy (NACT) prior to radical hysterectomy compared to those who did not receive NACT before surgery.
Materials And Methods: This is a multicenter study including data of 6 gynecological oncology departments. The study is approved from one of the institution's local ethics committee.
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