Obesity across the lifespan in congenital heart disease survivors: Prevalence and correlates.

Heart Lung

Center for Biobehavioral Health, Nationwide Children's Hospital, Near East Office Building, 3(rd) Floor, 431 S. 18(th) St., Columbus, OH 43205, USA; Department of Pediatrics, The Ohio State University, 370 W. 9th Ave., Columbus, OH 43210, USA; Division of Epidemiology, College of Public Health, The Ohio State University, 1841 Neil Ave, Columbus, OH 43210, USA. Electronic address:

Published: March 2021

Background: Congenital heart disease (CHD) survivors are at risk for cardiovascular comorbidities exacerbated by obesity.

Objectives: Determine relationships between overweight/obesity and medical factors across the lifespan of CHD.

Methods: Lesion severity, weight, blood pressure, cardiac and other comorbidities, and cardiac medications were abstracted from the medical records of 3790 CHD patients, aged ≥6 years, who attended CHD care in the Midwestern U.S.

Results: The proportion of patients with overweight/obesity increased across the lifespan, with 73% of adults affected by overweight/obesity. Obesity was more prevalent among patients with moderate lesions (29%). Overweight/obesity was associated with elevated blood pressure across age and lesion severity. Young adults with obesity and simple or moderate lesions had more comorbidities (simple: IRR = 3.1, moderate: IRR = 2.3) and cardiac medications (simple: IRR = 2.2, moderate: IRR = 1.7).

Conclusions: Obesity and its cardiovascular correlates are present across the lifespan for CHD survivors, highlighting the need for early prevention and intervention.

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Source
http://dx.doi.org/10.1016/j.hrtlng.2020.08.020DOI Listing

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