AI Article Synopsis
- Toll-like receptor ligands found in indoor dust can enhance the body's allergic response, specifically increasing the risk of peanut sensitization in mice.
- The study highlights that the timing of exposure to these environmental adjuvants is crucial; when mice are exposed to them in relation to peanut allergens can influence allergy development.
- Overall, the findings suggest that indoor dust may play a significant role in the rising prevalence of peanut allergies by acting as a trigger during critical exposure windows.
Article Abstract
Toll-like receptor ligands in indoor dust act as environmental adjuvants to promote sensitization to inhaled peanut in mice. The timing of exposure to environmental adjuvants relative to peanut is a determinant of peanut allergy development.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7855661 | PMC |
| http://dx.doi.org/10.1016/j.jaci.2020.09.011 | DOI Listing |
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