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Tools and techniques for illuminating the cell biology of zinc. | LitMetric

Tools and techniques for illuminating the cell biology of zinc.

Biochim Biophys Acta Mol Cell Res

Department of Biochemistry and BioFrontiers Institute, University of Colorado Boulder, 3415 Colorado Ave, Boulder, CO 80303, United States of America. Electronic address:

Published: January 2021

Zinc (Zn) is an essential micronutrient that is required for a wide variety of cellular processes. Tools and methods have been instrumental in revealing the myriad roles of Zn in cells. This review highlights recent developments fluorescent sensors to measure the labile Zn pool, chelators to manipulate Zn availability, and fluorescent tools and proteomics approaches for monitoring Zn-binding proteins in cells. Finally, we close with some highlights on the role of Zn in regulating cell function and in cell signaling.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680430PMC
http://dx.doi.org/10.1016/j.bbamcr.2020.118865DOI Listing

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