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Circulating Complex of Lipoprotein(a) and Proprotein Convertase Subtilisin/Kexin Type 9 in the Serum Measured by ELISA. | LitMetric
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Circulating Complex of Lipoprotein(a) and Proprotein Convertase Subtilisin/Kexin Type 9 in the Serum Measured by ELISA.

O A Razova O I Afanas'eva M G Egiazaryan E E Sherstyuk E A Klesareva S N Pokrovskii

Bull Exp Biol Med

National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow, Russia.

Published: September 2020

The presence of a complex of lipoprotein(a) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in the blood of healthy volunteers and patients with cardiovascular diseases was analyzed by ELISA. The levels of the complex varied in a wide range and did not depend on the concentrations of Lp(a) and PCSK9. Moreover, the complex was found not only in patients with cardiovascular diseases, but also in healthy volunteers, which can indicate physiological role of lipoprotein(a) as PCSK9 transporter.

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http://dx.doi.org/10.1007/s10517-020-04944-0DOI Listing

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