AI Article Synopsis
- * This study aimed to systematically review and analyze the relationship between maternal antenatal depression and neonatal Apgar scores, utilizing research from multiple reputable databases.
- * The analysis of 13 studies with over 12,000 women found that while antenatal depression raised the risk for a low Apgar score at 5 minutes, there was no significant difference in mean Apgar scores between babies born to depressed and non-depressed mothers.
Article Abstract
Introduction: Antenatal depression is common, but most women with the condition choose to remain untreated. The Apgar score, an important indicator of newborn health, has been reported to be influenced by antenatal depression; thus, maternal antenatal depression, as reflected by a poor Apgar score, may harm children's health.
Aim: To conduct a systematic review and meta-analysis to explore whether maternal antenatal depression is associated with the neonatal Apgar score.
Methods: We registered the protocol for this study with PROSPERO (CRD42019137585). We searched PubMed, Embase, Web of Science, and the Cochrane Library for published papers that reported the association between depression and Apgar score from inception to December 4, 2019. Two reviewers independently screened and selected the studies according to the inclusion and exclusion criteria, and extracted data according to the predesigned table. Stata version 12.0 software was used to analyze data.
Results: We finally identified 13 studies for inclusion, including a total of 12017 women. We did not find an association between antenatal depression and the 1 min Apgar score of neonates (mean difference= -0.03, 95% CI= -0.15-0.09) or the risk of a low Apgar score (OR=1.82, 95% CI=0.51 to 3.13). We found that antenatal depression increased the risk of a low Apgar score at 5 min (OR= 1.91, 95% CI= 1.23-2.59), but the association between the 5 min Apgar score and antenatal depression was not significant (mean difference= -0.001, 95% CI= -0.07-0.07). The results of the subgroup analyses also indicated that there was no association between the 5 min Apgar score and antenatal depression.
Conclusions: Antenatal depression increased the risk of a low 5 min Apgar score; however, we did not find a difference in the mean and distribution of neonatal Apgar scores of mothers with depression and mothers without depression.
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| http://dx.doi.org/10.1016/j.jad.2020.09.054 | DOI Listing |
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