Albendazole is a drug commonly used for treating many parasitoses. The primary mechanism of action is inhibition of microtubule polymerization binding to β-tubulin, similar to colchicine as a microtubule formation inhibitor. It is reasonable that these two antimitotic drugs can cause side effects such as alopecia and cytopenia by a similar mechanism. In the literature, only one albendazole-induced anagen effluvium has been reported. This article presents two cases of anagen effluvium that developed 2 weeks after oral albendazole administration, summarizes all cases reported to date, and offers recommendations for a diagnostic approach.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma.
Exp Dermatol
October 2024
Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Article Synopsis
- Hair follicles undergo a continuous cycle of growth (anagen), regression (catagen), and rest (telogen), with the time spent in each phase affecting hair length and health.
- Traditional beliefs suggest that 85%-90% of hair follicles are in the growth phase, but recent studies indicate that these values may not be accurate due to flaws in assessment methods.
- A new examination of hair follicles during hair transplants revealed that catagen follicles (7.5%) are more prevalent than previously thought, challenging the established belief about the distribution of hair follicles in different stages.
Hair Loss: Diagnosis and Treatment.
Am Fam Physician
September 2024
Boston University Chobanian and Avedisian School of Medicine, Boston, MA.
Article Synopsis
- Over 80 million people in the U.S. experience hair loss, classified mainly as nonscarring alopecias (diffuse, patterned, or focal), with androgenetic alopecia being the most common.
- Treatment options vary: minoxidil is the first line for patterned hair loss, while focal hair loss may require corticosteroids or oral antifungals depending on the cause.
- Hair loss can lead to anxiety, depression, and lower quality of life, emphasizing the importance of patient education on treatment options and realistic expectations.
The Effects of Environmental Pollutants and Exposures on Hair Follicle Pathophysiology.
Skin Appendage Disord
August 2024
Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Article Synopsis
- Environmental exposures negatively affect hair follicles (HFs), which are sensitive to contaminants absorbed through the skin or circulated in the bloodstream.
- Pollutants like particulate matter can cause inflammation and are linked to hair loss conditions such as alopecia areata, while substances like tobacco smoke and heavy metals also impact hair health.
- Research on how these environmental factors affect hair pathology is ongoing and highlights the need for more in-depth studies.
[Alopecia due to chemotherapeutics, hedgehog inhibitors, targeted antibody therapies and immune checkpoint inhibitors : Pathogenesis, clinical picture, diagnostics and prophylaxis].
Dermatologie (Heidelb)
June 2024
Campus Kiel, Klinik für Dermatologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.
Article Synopsis
- * Chemotherapy-induced hair loss is quite common, affecting up to 65% of patients, often starting 1-3 weeks into treatment, but it is usually reversible.
- * Preventative measures like scalp cooling can be effective during chemotherapy, and it's recommended to connect patients early with support groups and resources for wigs if hair loss is anticipated.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!