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| http://dx.doi.org/10.1093/ehjcr/ytaa123 | DOI Listing |
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A data-driven model of disability progression in progressive multiple sclerosis.
Brain Commun
December 2024
Department of Health Sciences (DISSAL), Università di Genova, 16132 Genoa, Italy.
This study applies the Gaussian process progression model, a Bayesian data-driven disease progression model, to analyse the evolution of primary progressive multiple sclerosis. Utilizing data from 1521 primary progressive multiple sclerosis participants collected within the International Progressive Multiple Sclerosis Alliance Project, the analysis includes 18 581 longitudinal time-points (average follow-up time: 28.2 months) of disability assessments including the expanded disability status scale, symbol digit modalities, timed 25-foot-walk, 9-hole-peg test and of MRI metrics such as T1 and T2 lesion volume and normalized brain volume.
View Article and Find Full Text PDFThe Investigation of the Relationship Between Individual Pain Perception, Brain Electrical Activity, and Facial Expression Based on Combined EEG and Facial EMG Analysis.
J Pain Res
January 2025
Department of Rehabilitation Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Purpose: Pain is a multidimensional, unpleasant emotional and sensory experience, and accurately assessing its intensity is crucial for effective management. However, individuals with cognitive impairments or language deficits may struggle to accurately report their pain. EEG provides insight into the neurological aspects of pain, while facial EMG captures the sensory and peripheral muscle responses.
View Article and Find Full Text PDFPost-laparoscopic Shoulder Pain Management: A Narrative Review.
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Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, People's Republic of China.
Purpose Of Review: Post-laparoscopic shoulder pain (PLSP) can slow patient recovery and extend hospital stays, making its management crucial for patients undergoing laparoscopic surgery. Current consensus guidelines say little about how to prevent or manage PLSP. In this context, a multimodal approach to PLSP management that maybe extend beyond the pharmaceutical interventions currently employed.
View Article and Find Full Text PDFMultimodal deep ensemble classification system with wearable vibration sensor for detecting throat-related events.
NPJ Digit Med
January 2025
Department of Electrical Engineering, Pohang University of Science and Technology, Pohang, Korea.
Dysphagia, a swallowing disorder, requires continuous monitoring of throat-related events to obtain comprehensive insights into the patient's pharyngeal and laryngeal functions. However, conventional assessments were performed by medical professionals in clinical settings, limiting persistent monitoring. We demonstrate feasibility of a ubiquitous monitoring system for autonomously detecting throat-related events utilizing a soft skin-attachable throat vibration sensor (STVS).
View Article and Find Full Text PDFBackground: Annually, approximately 7.6 million individuals experience a new ischemic stroke, and roughly 25% of all ischemic strokes are cardiogenic in origin, carrying a high risk of recurrence, death and disability. To prevent future ischemic strokes, especially in younger individuals, it is crucial to detect and treat direct and indirect cardioembolic sources.
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