Using a model developed previously by the authors, a risk assessment was conducted to predict the change in the risk of ASF entering Japan as a result of the coronavirus pandemic in humans. The monthly probability of ASF entering Japan through illegal importation of pig products from China was calculated to be 4.2% (90% prediction interval: 0.0%-24.9%) in January, 0.45% (0%-2.5%) in February, 0.03% (0%-0.2%) in March and 0.0002% (0%-0.001%) in April, 0.00005% (0%-0.0003%) in May and 0.0009% (0%-0.005%) in June 2020 indicating a significant decline in the risk of ASF entry into Japan from China. The decline was attributed to a decrease in the number of air travellers from China and amount of restaurant food waste.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/tbed.13836 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Acute skin failure knowledge, attitudes and practices amongst intensive care unit nurses in China: A multicentre cross-sectional survey.
Int Wound J
January 2025
Intensive Care Unit, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Purpose: To investigate the knowledge, attitudes and practices of intensive care unit (ICU) nurses regarding acute skin failure (ASF) and analyse the influencing factors thereof.
Methods: From 22 December 2023 to 24 January 2024, a cross-sectional study was conducted amongst ICU nurses from 21 hospitals in eight provinces in China. The ASF knowledge, attitude and practice scores were determined using questionnaires, and multiple linear regression was used for further analysis.
Identification of cepharanthine as an effective inhibitor of African swine fever virus replication.
Emerg Microbes Infect
December 2024
One Health Laboratory, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, People's Republic of China.
African swine fever virus (ASFV) causes highly contagious swine disease, African swine fever (ASF), thereby posing a severe socioeconomic threat to the global pig industry and underscoring that effective antiviral therapies are urgently required. To identify safe and efficient anti-ASFV compounds, a natural compound library was screened by performing an established cell-based ELISA in an ASFV-infected porcine alveolar macrophage (PAM) model. In total, 6 effective anti-ASFV compounds with low cytotoxicity were identified.
View Article and Find Full Text PDFCD38 in SLE CD4 T cells promotes Ca flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane.
Nat Commun
September 2024
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
CD38 has emerged as a potential therapeutic target for patients with systemic lupus erythematosus (SLE) but it is not known whether CD38 alters CD4 T cell function. Using primary human T cells and CD38-sufficient and CD38-deficient Jurkat T cells, we demonstrate that CD38 shifts the T cell lipid profile of gangliosides from GM3 to GM2 by upregulating B4GALNT1 in a Sirtuin 1-dependent manner. Enhanced expression of GM2 causes ER stress by enhancing Ca flux through the PLCγ1-IP3 pathway.
View Article and Find Full Text PDFGenome-wide characterization of structure variations in the Xiang pig for genetic resistance to African swine fever.
Virulence
December 2024
Institute of Agro-Bioengineering, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Life Sciences, College of Animal Science, Guizhou University, Guiyang, Guizhou Province, China.
African swine fever (ASF) is a rapidly fatal viral haemorrhagic fever in Chinese domestic pigs. Although very high mortality is observed in pig farms after an ASF outbreak, clinically healthy and antibody-positive pigs are found in those farms, and viral detection is rare from these pigs. The ability of pigs to resist ASF viral infection may be modulated by host genetic variations.
View Article and Find Full Text PDFA genome-wide CRISPR/Cas9 knockout screen identifies TMEM239 as an important host factor in facilitating African swine fever virus entry into early endosomes.
PLoS Pathog
July 2024
State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-reference Laboratory, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
African swine fever (ASF) is a highly contagious, fatal disease of pigs caused by African swine fever virus (ASFV). The complexity of ASFV and our limited understanding of its interactions with the host have constrained the development of ASFV vaccines and antiviral strategies. To identify host factors required for ASFV replication, we developed a genome-wide CRISPR knockout (GeCKO) screen that contains 186,510 specific single guide RNAs (sgRNAs) targeting 20,580 pig genes and used genotype II ASFV to perform the GeCKO screen in wild boar lung (WSL) cells.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!