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Estimation of microbiota and interleukin-1 beta in tears and conjunctival secretions of patients with ocular defects after using unilateral ocular prosthesis.
J Prosthet Dent
January 2025
Professor, Department of Ophthalmology, King George's Medical University, Lucknow, India.
Statement Of Problem: Clinical studies evaluating the levels of interleukin-1 beta (IL-1β) in tears and conjunctival secretions of patients with ocular defects after using ocular prostheses are lacking. Therefore, a comparative evaluation of IL-1β levels in the defective eye before and after placement of an ocular prosthesis is needed.
Purpose: The purpose of this clinical study was to compare the microbiota and IL-1β in tears and conjunctival secretions of patients with an ocular defect after using an ocular prosthesis.
Reduction in bacterial culture positivity rates at a human milk bank facility of a tertiary care hospital: a quality improvement initiative.
BMJ Open Qual
January 2025
Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, Maharashtra, India.
Background: Human milk banks (HMBs) offer the best feed for neonates after mother's own milk (MOM), especially when MOM is insufficient. Although HMBs are founded on standard protocols, contamination and wastage of milk due to positive milk cultures remain a problem. Present study was planned as a quality improvement (QI) initiative to reduce culture rates at the HMB.
View Article and Find Full Text PDFEvaluation of Cognitive Functions in People Living with HIV Before and After COVID-19 Infection.
Viruses
January 2025
1st Department of Internal Medicine, Laiko General Hospital, 11527 Athens, Greece.
Background: Cognitive function decline is a problem in aging people living with HIV (PLWHIV). COVID-19 infection is associated with neuropsychiatric manifestations that may persist. The aim of our study was to evaluate cognitive function in PLWHIV before and after COVID-19 infection.
View Article and Find Full Text PDFPhage M198 and Its Therapeutic Potential.
Viruses
January 2025
Laboratory of Molecular Biology, G. Eliava Institute of Bacteriophages, Microbiology and Virology, 0160 Tbilisi, Georgia.
The rapid worldwide spread of antibiotic resistance is quickly becoming an increasingly concerning problem for human healthcare. Non-antibiotic antibacterial agents are in high demand for many Gram-negative bacterial pathogens, including . -targeting phages are among the most promising alternative therapy options.
View Article and Find Full Text PDFModeling BK Virus Infection in Renal Transplant Recipients.
Viruses
December 2024
Duke Center for Human Systems Immunology, Duke University, Durham, NC 27701, USA.
Kidney transplant recipients require a lifelong protocol of immunosuppressive therapy to prevent graft rejection. However, these same medications leave them susceptible to opportunistic infections. One pathogen of particular concern is human polyomavirus 1, also known as BK virus (BKPyV).
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