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Risk Factors Associated with Recurrent Infection. | LitMetric

Risk Factors Associated with Recurrent Infection.

Healthcare (Basel)

Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 29 N. Jiga St., 410028 Oradea, Romania.

Published: September 2020

AI Article Synopsis

Article Abstract

(CD) is responsible for nosocomial diarrhea syndrome with possible severe progression. Recurrence of the disease induces higher health system costs, as well as exposes patients to additional health risks. Patients with recurrence of this disease are difficult to identify, so the purpose of this study is to quantify various demographic, clinical, and treatment factors that could prevent further progression to recurrence of the disease. In the period 2018-2019, about 195 patients were diagnosed with more than one episode of CDI in the three months following the first episode. The recurrence rate for CDI was 53.84% (60.95% for one episode and 39.05% for multiple episodes). Most commonly afflicted were 60-69-year-old patients, or those with higher Charlson Comorbidity Index (CCI). Multiple analyses associated cardiovascular (odds ratios (OR) = 3.02, 95% confidence intervals (CI) = 1.23-7.39, = 0.015), digestive (OR = 3.58, 95% CI = 1.01-12.63, = 0.047), dementia (OR = 3.26, 95% CI = 1.26-8.41, = 0.014), immunosuppressive (OR = 3.88, 95% CI = 1.34-11.21, = 0.012) comorbidities with recurrences. Risk factor identification in the first episode of CDI could lead to the implementation of treatment strategies to improve the patients' quality of life affected by this disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551610PMC
http://dx.doi.org/10.3390/healthcare8030352DOI Listing

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