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| http://dx.doi.org/10.1016/j.infbeh.2020.101494 | DOI Listing |
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Electrochemical biosensing in oncology: a review advancements and prospects for cancer diagnosis.
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Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
Early and precise diagnosis of cancer is pivotal for effective therapeutic intervention. Traditional diagnostic methods, despite their reliability, often face limitations such as invasiveness, high costs, labor-intensive procedures, extended processing times, and reduced sensitivity for early-stage detection. Electrochemical biosensing is a revolutionary method that provides rapid, cost-effective, and highly sensitive detection of cancer biomarkers.
View Article and Find Full Text PDFIntegration of Photodiagnosis and Therapy Guided by Micro/Nanorobots.
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Engineering Research Center for Pharmaceuticals and Equipments of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, China.
Micro/Nanorobots(MNRs)integrated with phototherapy represent an emerging approach to cancer treatment and hold significant potential for addressing bacterial infections, neurological disorders, cardiovascular diseases, and related conditions. By leveraging micro/nanoscale motor systems in conjunction with phototherapy, these robots enable real-time guidance and monitoring of therapeutic processes, improving drug delivery precision and efficiency. This integration not only enhances the effectiveness of phototherapy but also minimizes damage to surrounding healthy tissues.
View Article and Find Full Text PDFEffectiveness of Switching from Multiple-Inhaler to Once-Daily Single-Inhaler Triple Therapy in Patients with COPD in a Real-World Setting in Japan.
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Real World Data Analytics, Japan Development, GSK, Tokyo, Japan.
Purpose: Following the relatively recent introduction of single-inhaler triple therapies in Japan, this study compared the effectiveness of switching from multiple-inhaler triple therapy (MITT) to once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) by investigating COPD exacerbations and adherence among patients with chronic obstructive pulmonary disease (COPD) in Japan.
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Gut microbiota therapy in gastrointestinal diseases.
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Medicine and Engineering Interdisciplinary Research Laboratory of Nursing & Materials, Nursing Key Laboratory of Sichuan Province, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.
The human gut microbiota, consisting of trillions of microorganisms, plays a crucial role in gastrointestinal (GI) health and disease. Dysbiosis, an imbalance in microbial composition, has been linked to a range of GI disorders, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), celiac disease, and colorectal cancer. These conditions are influenced by the interactions between the gut microbiota, the host immune system, and the gut-brain axis.
View Article and Find Full Text PDFControl of medical digital twins with artificial neural networks.
Philos Trans A Math Phys Eng Sci
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Department of Medicine, Laboratory for Systems Medicine, University of Florida, Gainesville, FL, USA.
The objective of precision medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be personalized and dynamically updated to incorporate patient-specific data. Certain aspects of human biology, such as the immune system, are not easily captured with physics-based models, such as differential equations.
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