Herein, an efficient visible-light-mediated N-H heteroarylation via remote heteroaryl ipso-migration has been accomplished. Moderate to good yields were obtained with good functional group tolerance. Moreover, a simple and readily available organic photoredox catalyst was employed, avoiding the use of complex and costly noble metal compounds.
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Article Synopsis
- The text discusses a new method for functionalizing complex molecules by targeting both reactive and inert sites simultaneously, a challenging task in chemistry.
- The authors present a modular approach that uses a combination of radical additions, functional group migrations, and dual catalysis (photo and cobalt) to achieve precise control over where reactions occur.
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