Contrast-induced sialadenitis (CIS) is a rare, delayed pseudoallergic reaction from iodine containing contrast. Previously reported cases of CIS demonstrated that the two major salivary glands (parotid and submandibular) can be affected. The initial encounter of this entity can raise alarms to physicians as the differential diagnoses include serious infectious and inflammatory conditions such as Ludwig's angina and angioedema. Subsequently, it may lead to unnecessary testing and increased healthcare cost. Here we present a 60-year-old male who presented with bilateral sublingual gland swelling following exposure to iodinated contrast. With timely diagnosis by the otolaryngologist, the patient received conservative management that led to a full resolution within a few days. To date, this is the first case of CIS only involving the sublingual glands. We conclude that CIS can involve any of the major salivary glands.
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http://dx.doi.org/10.1155/2020/8851382 | DOI Listing |
AJNR Am J Neuroradiol
September 2024
From the Department of Neurosurgery (S.H.L., O.K.K., Y.D.K., Y.L., C.W.O., J.S.B., S.U.L., S.P.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea; Department of Neurosurgery (O.K.K., C.W.O., J.S.B., S.P.B.), Seoul National University College of Medicine, Seoul, Korea;Department of Neurosurgery (M.Y.K.), Keimyung University Dongsan Hospital, Daegu, Korea.
Background And Purpose: Swelling of the salivary glands, known as contrast-induced sialadenitis (CIS), is an adverse reaction to iodide contrast agents. However, the incidence and risk factors of CIS after therapeutic neuroendovascular procedures have not yet been established.
Materials And Methods: Demographic and procedural factors that may influence the development of CIS were retrospectively analyzed to identify the incidence and risk factors of this condition.
Rev Port Cardiol
January 2025
Allergology Department, Hospital IMED Valencia, Burjassot, Spain.
Mymensingh Med J
July 2024
Dr Samsun Nahar, Associate Consultant (Cardiology), United Hospital Limited, Dhaka, Bangladesh; E-mail:
Indian J Otolaryngol Head Neck Surg
September 2023
Department of Neurology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Unlabelled: Background: Contrast Induced Sialadenitis or Iodide Mumps refers to non-suppurative inflammation of salivary glands following intravenous iodinated contrast administration. It is a rare adverse effect of iodinated contrast with only a few cases reported worldwide. It is hypothesized to be an idiosyncratic reaction due to toxic accumulation of iodine in salivary glands.
View Article and Find Full Text PDFActa Otolaryngol
January 2023
Unit of Laryngology-Head & Neck Surgery, Department of Otorhinolaryngology, La Fe University and Polytechnic Hospital, University of Valencia, Valencia, Spain.
Background: Iodine contrast-induced sialadenitis (CIS) is an uncommon adverse effect to iodine-containing contrast exposition. There is scarce literature about its clinical course and demography.
Objectives: (1) To determine the clinical course and management of CIS.
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