AI Article Synopsis
- - Single-cell whole-genome amplification helps researchers explore the genetic structure of Waldenström’s macroglobulinemia, a type of cancer.
- - The genetic mutations found in the cells may be linked to changes in genes responsible for DNA repair and tumor suppression.
- - Understanding these mutations can provide insights into the disease's progression and potential treatment strategies.
Article Abstract
Single-cell whole-genome amplification can be used to interrogate the genomic architecture of Waldenström’s macroglobulinemia. The mutational signature of cells may be associated with alterations in DNA repairing genes and tumor suppressors.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509875 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2020001775 | DOI Listing |
Publication Analysis
Top Keywords
comparative genomics
4
genomics cxcr4mut
4
cxcr4mut cxcr4wt
4
cxcr4wt single
4
single cells
4
cells waldenström's
4
waldenström's macroglobulinemia
4
macroglobulinemia single-cell
4
single-cell whole-genome
4
whole-genome amplification
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!