To determine phenotypically the anti quorum-sensing (QS) activity of 30 volatile organic products (VOPs) through the inhibition of swarming motility and pyoverdine production in . Twenty-four essential oils and six small volatile organic compounds randomly selected were screened for their anti-QS activity by violacein inhibition on . The VOPs with positive results were subsequently evaluated for swarming motility and pyoverdine production on determining the colony diameter and fluorescence under UV light, respectively. Fifty percent of VOPs tested showed strong violacein inhibition, 40% presented anti-swarming activity and 33% inhibited pyoverdine production. Our data demonstrate that VOPs have a great potential to inhibit virulence factors mediated by QS in .
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http://dx.doi.org/10.2217/fmb-2020-0033 | DOI Listing |
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