•We report here a case of JC virus granule cell neuronopathy associated with Ruxolitinib•It is worthwhile considering the possibility of JCV-GCN in myelofibrosis patients receiving ruxiolitinib, who present with progressive cerebellar symptoms and cerebellar atrophy.•Combination therapy using mefloquine and mirtazapine may be an effective treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486434PMC
http://dx.doi.org/10.1016/j.ensci.2020.100269DOI Listing

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