AI Article Synopsis
- Vulvar cancer is rare but more frequently diagnosed in postmenopausal women due to estrogen deficiency, while young women often develop it due to HPV infection.
- HIV-positive women are at a higher risk for vulvar cancer because they often have higher rates of HPV infection.
- A biopsy and pathological analysis are essential for diagnosing suspected vulvar lesions, as illustrated by a reported case of vulvar squamous cell carcinoma in an HIV-1-positive patient experiencing treatment failure.
Article Abstract
Vulvar cancer has been rarely reported in the literature. In young women, it is most often caused by human papillomavirus (HPV), whereas in postmenopausal women, in whom this cancer is more common, it would be caused by estrogen deficiency. Moreover, HIV infection increases the risk of developing vulvar cancer in HIV-positive women as a consequence of the high prevalence of HPV infection in these subjects. Thus, in patients with suspected vulva lesion, biopsy followed by anatomo-pathological examination should be performed in order to establish the diagnosis. We here report a case of vulvar squamous cell carcinoma in a HIV-1-positive patient with first-line antiretroviral therapy (ARV) failure.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467881 | PMC |
| http://dx.doi.org/10.11604/pamj.2020.36.181.20628 | DOI Listing |
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