AI Article Synopsis
- SARS-CoV-2 is the virus responsible for the COVID-19 pandemic, characterized by a lengthy incubation period and high transmissibility, posing significant global health risks.
- Detection of the virus's nucleic acid is crucial for quickly identifying cases and controlling the spread of the disease.
- As of August 2020, China approved 15 nucleic acid detection kits, primarily using RT-qPCR technology, with the article reviewing their principles, timing, and pros/cons to aid in better screening and diagnosis of COVID-19 and related infections.
Article Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an ongoing pandemic of new coronavirus pneumonia (corona virus disease 2019, COVID-19). The virus has a long incubation period and strong infectivity, which poses a major threat to global health and safety. Detection of SARS-CoV-2 nucleic acid lies at the center of rapid detection of COVID-19, which is instrumental for mitigation of the ongoing pandemic. As of August 17, 2020, The National Medical Products Administration in China has approved 15 new coronavirus nucleic acid detection kits, 10 kits of which are based on reverse transcription-real-time quantitative PCR (RT-qPCR) technology. The remaining kits use five molecular diagnostic technologies different from RT-qPCR. This article reviews the principles, reaction time, advantages and disadvantages of above 15 detection kits, in order to provide references for rapid screening, diagnosis, prevention and control of COVID-19 and similar infectious diseases.
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| http://dx.doi.org/10.16288/j.yczz.20-189 | DOI Listing |
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