Secondary hyperparathyroidism is one of the most common complications of chronic kidney failure. If prolonged, parathyroid hormone release gains autonomy and tertiary hyperparathyroidism with parathyroid adenoma or hyperplasia can be develop. Tertiary hyperparathyroidism is associated with increased risk of mortality and morbidity; thus, treatment is recommended. Medical treatment includes phosphate binders, vitamin D analogues, and calcimimetic agents. Most cases of tertiary hyperparathyroidism can be controlled with medical treatment. When medical treatment options prove insufficient, parathyroidectomy is recommended. However, recurrence after parathyroidectomy is possible, which requires an alternative treatment. We present our percutaneous embolization experience, which has not been tried in the treatment of tertiary hyperparathyroidism in renal transplantation patients diagnosed with tertiary hyperparathyroidism.
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| http://dx.doi.org/10.1016/j.transproceed.2020.08.033 | DOI Listing |
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Article Synopsis
- Secondary hyperparathyroidism (sHPT) is common in chronic kidney disease (CKD) patients, with many developing tertiary hyperparathyroidism (tHPT) after kidney transplantation.
- A meta-analysis of 12 studies investigated how parathyroidectomy (surgery to remove the parathyroid glands) affects kidney graft function one year after the procedure.
- Results showed a decline in kidney function, indicated by lower glomerular filtration rate and higher serum creatinine levels, suggesting that while calcium and parathyroid hormone levels normalized, the risk of graft loss increases after parathyroidectomy.
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